Evidence map›Paper›PMID 35781042›Full record

ArticleHeart rhythm2022

The need for a subsequent transvenous system in patients implanted with subcutaneous implantable cardioverter-defibrillator.

Alessio Gasperetti, Marco Schiavone, Julia Vogler, Mikael Laredo, Fabian Fastenrath, Pietro Palmisano, Matteo Ziacchi, Andrea Angeletti, Gianfranco Mitacchione, Lukas Kaiser and 23 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Heart rhythm, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Impact of ventricular tachycardia ablation in subcutaneous implantable cardioverter defibrillator carriers: a multicentre, international analysis from the iSUSI project.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Trial
  2. Implantable Defibrillators: Which Is the Best Device for Each Patient?Journal of cardiovascular electrophysiology · 2025
    Review
  3. Sex differences among subcutaneous implantable cardioverter-defibrillator recipients: a propensity-matched, multicentre, international analysis from the i-SUSI project.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Observational
  4. Comparison of automated subcutaneous defibrillator screening between different pacing sites in cardiac pacing device carriers.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  5. S-ICD Implantation "Tips and Tricks".Reviews in cardiovascular medicine · 2023
    Review
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

33 authors.

Alessio GasperettiCardiology Unit, Luigi Sacco University Hospital, Milan, Italy; Università degli Studi di Milano, Milan, Italy; Johns Hopkins University, Baltimore, Maryland; Department of Biomedical Sciences and Public Health, Marche Polytechnic University, Ancona, Italy. Electronic address: alessio.gasperetti93@gmail.com.
Marco SchiavoneUniversità degli Studi di Milano, Milan, Italy.
Julia VoglerDepartment of Rhythmology, Herzzentrum Lubeck, Lubeck, Germany.
Mikael LaredoAPHP, Hôpital Pitié Salpêtrière, Paris, France.
Fabian FastenrathCardiology Unit, University Medical Centre Mannheim, Manheim, Germany.
Pietro PalmisanoCardiology Unit, "Card. G. Panico" Hospital, Tricase, Italy.
Matteo ZiacchiCardiology Unit, IRCCS, Department of Experimental, Diagnostic and Specialty Medicine, Sant'Orsola Hospital, University of Bologna, Bologna, Italy.
Andrea AngelettiCardiology Unit, IRCCS, Department of Experimental, Diagnostic and Specialty Medicine, Sant'Orsola Hospital, University of Bologna, Bologna, Italy.
Gianfranco MitacchioneCardiology Unit, Luigi Sacco University Hospital, Milan, Italy; Cardiology Unit, Spedali Civili Brescia, Brescia, Italy.
Lukas KaiserSt. George Klinik Asklepios, Hamburg, Germany.
Paolo CompagnucciDepartment of Biomedical Sciences and Public Health, Marche Polytechnic University, Ancona, Italy; Cardiology and Arrhythmology Clinic, University Hospital Ospedali Riuniti, Ancona, Italy.
Alexander BreitensteinUniversity Hospital Zurich, Zurich, Switzerland.
Roberto ArosioUniversità degli Studi di Milano, Milan, Italy.
Francesco VitaliCardiological Center, S. Anna University Hospital, Ferrara, Italy.
Silvana De BonisDepartment of Cardiology, Castrovillari Hospital, Cosenza, Italy.
Francesco PicarelliDepartment of Cardiology, Campus Biomedico, Rome, Italy.
Michela CasellaCardiology and Arrhythmology Clinic, University Hospital Ospedali Riuniti, Ancona, Italy.
Luca SantiniCardiology Unit, Ospedale G.B. Grassi, Ostia, Italy.
Carlo PignalberiCardiology Unit, Ospedale San Filippo Neri, Rome, Italy.
Carlo LavalleCardiology Unit, Policlinico Umberto I, Rome, Italy.
Ennio PisanòCardiac Electrophysiology Unit, Vito Fazzi Hospital, Lecce, Italy.
Danilo RicciardiDepartment of Cardiology, Campus Biomedico, Rome, Italy.
Leonardo CalòCardiology Unit, Policlinico Casilino, Rome, Italy.
Antonio CurnisCardiology Unit, Spedali Civili Brescia, Brescia, Italy.
Matteo BertiniCardiological Center, S. Anna University Hospital, Ferrara, Italy.
Simone GullettaArrhythmology and Electrophysiology Unit, San Raffaele Hospital, IRCCS, Milan, Italy.
Antonio Dello RussoDepartment of Biomedical Sciences and Public Health, Marche Polytechnic University, Ancona, Italy; Cardiology and Arrhythmology Clinic, University Hospital Ospedali Riuniti, Ancona, Italy.
Nicolas BadencoAPHP, Hôpital Pitié Salpêtrière, Paris, France.
Claudio TondoHeart Rhythm Center, Monzino Cardiology Center, IRCCS, Milan, Italy.
Jürgen KuschykCardiology Unit, University Medical Centre Mannheim, Manheim, Germany.
Roland TilzDepartment of Rhythmology, Herzzentrum Lubeck, Lubeck, Germany; German Center for Cardiovascular Research (DZHK), Partner Site Hamburg/Kiel/Lübeck, Lübeck, Germany.
Giovanni B ForleoCardiology Unit, Luigi Sacco University Hospital, Milan, Italy.
Mauro BiffiCardiology Unit, IRCCS, Department of Experimental, Diagnostic and Specialty Medicine, Sant'Orsola Hospital, University of Bologna, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe absence of pacing capabilities may reduce the appeal of subcutaneous implantable cardioverter-defibrillator (S-ICD) devices for patients at risk for conduction disorders or with antitachycardia pacing (ATP)/cardiac resynchronization (CRT) requirements. Reports of rates of S-ICD to transvenous implantable cardioverter-defibrillator (TV-ICD) system switch in real-world scenarios are limited.

objectiveThe purpose of this study was to investigate the need for a subsequent transvenous (TV) device in patients implanted with an S-ICD and its predictors.

methodsAll patients implanted with an S-ICD were enrolled from the multicenter, real-world iSUSI (International SUbcutaneouS Implantable cardioverter defibrillator) Registry. The need for a TV device and its clinical reason, and appropriate and inappropriate device therapies were assessed. Logistic regression with Firth penalization was used to assess the association between baseline and procedural characteristics and the overall need for a subsequent TV device.

resultsA total of 1509 patients were enrolled (age 50.8 ± 15.8 years; 76.9% male; 32.0% ischemic; left ventricular ejection fraction 38% [30%-60%]). Over 26.5 [13.4-42.9] months, 155 (10.3%) and 144 (9.3%) patients experienced appropriate and inappropriate device therapies, respectively. Forty-one patients (2.7%) required a TV device (13 bradycardia; 10 need for CRT; 10 inappropriate shocks). Body mass index (BMI) >30 kg/m

conclusionA low rate (2.7%) of conversion from S-ICD to a TV device was observed at follow-up, with need for antibradycardia pacing, ATP, or CRT being the main reasons. BMI >30 kg/m

Indexed as

Defibrillators, ImplantableRenal Insufficiency, ChronicAdenosine TriphosphateAdultAgedDeath, Sudden, CardiacFemaleHumansMaleMiddle AgedRetrospective StudiesStroke VolumeTreatment OutcomeVentricular Function, LeftAdenosine TriphosphateNeed for antitachycardia pacingSubcutaneous implantable cardioverter-defibrillatorSubcutaneous implantable cardioverter-defibrillator complicationsSudden cardiac deathTransvenous implantable cardioverter-defibrillator upgrade

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.