Evidence map›Paper›PMID 35780756›Full record

ArticleCortex; a journal devoted to the study of the nervous system and behavior2022

Cognitive impairment in people with previous COVID-19 infection: A scoping review.

Margherita Bertuccelli, Luciana Ciringione, Maria Rubega, Patrizia Bisiacchi, Stefano Masiero, Alessandra Del Felice

Abstract readScoping Review
In one paragraph

Article in Cortex; a journal devoted to the study of the nervous system and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
53citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

53 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Definitions and symptoms of the post-COVID syndrome: an updated systematic umbrella review.European archives of psychiatry and clinical neuroscience · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. A digital intervention for cognitive deficits following COVID-19: a randomized clinical trial.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Trial
  8. Episodic memory deficits and processes in post-COVID condition.European archives of psychiatry and clinical neuroscience · 2026
    Article
  9. Article
  10. Observational
  11. Article
  12. Article
  13. Article
  14. Olfactory Dysfunction and Cognitive Decline: Are They Related?Current allergy and asthma reports · 2025
    Review
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  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Margherita BertuccelliDepartment of Neuroscience, Section of Rehabilitation, University of Padova, Via Giustiniani 3, 35128 Padova, Italy; Padova Neuroscience Center, University of Padova, 35131 Padova, Italy.
Luciana CiringioneDepartment of Neuroscience, Section of Rehabilitation, University of Padova, Via Giustiniani 3, 35128 Padova, Italy.
Maria RubegaDepartment of Neuroscience, Section of Rehabilitation, University of Padova, Via Giustiniani 3, 35128 Padova, Italy.
Patrizia BisiacchiPadova Neuroscience Center, University of Padova, 35131 Padova, Italy; Department of General Psychology, University of Padova, Padova, Italy.
Stefano MasieroDepartment of Neuroscience, Section of Rehabilitation, University of Padova, Via Giustiniani 3, 35128 Padova, Italy; Padova Neuroscience Center, University of Padova, 35131 Padova, Italy.
Alessandra Del FeliceDepartment of Neuroscience, Section of Rehabilitation, University of Padova, Via Giustiniani 3, 35128 Padova, Italy; Padova Neuroscience Center, University of Padova, 35131 Padova, Italy. Electronic address: alessandra.delfelice@unipd.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 is a worldwide public health issue. Almost 2 years into the pandemic, the persistence of symptoms after the acute phase is a well-recognized phenomenon. We conducted a scoping review to map cognitive domain impairments, their frequency, and associated psycho-affective disorders in people with a previous COVID-19 infection. We searched PubMed/MEDLINE, Scopus, and PsycInfo to identify relevant reports published between December 1, 2019 and February 21, 2022. We followed the PRISMA (Preferred-Reporting-Items-for-Systematic-Reviews-and-Meta-Analyses) extension for scoping review guidelines. Three independent reviewers selected and charted 25 records out of 922. Memory, attention, and executive functions appeared to be the most affected domains. Delayed recall and learning were the most impaired domains of memory. Among the executive functions, abstraction, inhibition, set shifting, and sustained and selective attention were most commonly impaired. Language and visuo-spatial abilities were rarely affected, although this finding might be biased by the scarcity of reports. Neurological and respiratory conditions were often reported in association with cognitive deficits. Results on psycho-affective conditions were inconclusive due to the low frequency of reported data. Admission to an intensive care unit is not related to cognitive deficits. This review highlighted a potential effect of a previous post-COVID-19 infection on a pattern of memory, attention, and executive functions impairments. These findings need to be confirmed on larger cohorts with comprehensive neuropsychological batteries and correlated to neurophysiological and neurobiological substrates.

Indexed as

Cognitive DysfunctionCOVID-19HumansPandemicsSARS-CoV-2Cognitive impairmentCoronavirusLong-COVID-19 syndromeNeuropsychological abnormalitiesPost-COVID-19 syndromeSARS-CoV-2

Identifiers

PMID35780756
PMCPMC9187867

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.