Evidence map›Paper›PMID 35780654›Full record

ReviewCurrent opinion in chemical biology2022

The chemical biology of NAD

Janneke D Icso, Paul R Thompson

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in chemical biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Review
  3. SARM1 Exacerbates Pressure Overload-Induced Cardiac Hypertrophy and Heart Failure by Enhancing NADFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. NADAntioxidants & redox signaling · 2023
    Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Janneke D IcsoProgram in Chemical Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, USA.
Paul R ThompsonProgram in Chemical Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA; Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA, USA. Electronic address: Paul.Thompson@umassmed.edu.
University of Massachusetts Chan Medical School · US

Funding

Chemical probes to decipher PAD biologyR35GM118112 · NIGMS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Paul R Thompson · 2016 to 2026
$9.5M
Training in the Molecular Basis of Autoimmunity and AutoinflammationT32AI132152 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Katherine A. Fitzgerald, Ann Marshak-Rothstein · 2018 to 2026
$1.6M
Pathogen sensing by nuclear hormone receptors in C. elegans intestinal epithelial cellsF30AI150127 · NIAID · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI PETERSON, NICHOLAS · 2020 to 2023
$132k
Investigating the Activation Mechanism of SARM1 during Axon DegenerationF31NS122423 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI DOEDEE, JANNEKE · 2021 to 2023
$97k
A chemical biology approach to studying the role of SARM1 in a novel degradative pathwayF31NS108610 · NINDS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI LORING, HEATHER STARR · 2018 to 2020
$80k
NIAID NIH HHS F30 AI150127NIAID NIH HHS T32 AI132152NIGMS NIH HHS R35 GM118112NINDS NIH HHS F31 NS108610NINDS NIH HHS F31 NS122423
6 · The paper itself

Abstract

During axon degeneration, NAD

Indexed as

Armadillo Domain ProteinsNicotinamide-Nucleotide AdenylyltransferaseAnimalsAxonsBiologyCytoskeletal ProteinsMiceNADArmadillo Domain ProteinsCytoskeletal ProteinsNADNicotinamide-Nucleotide AdenylyltransferaseNmnat2 protein, mouseSARM1 protein, mouseAxon degenerationHydrolaseNAD(+)NeuropathySARM1Wallerian degeneration

Identifiers

PMID35780654
PMCPMC10084848
OpenAlexW4283738867

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.