Evidence map›Paper›PMID 35780440›Full record

ArticleCardiology and therapy2022

Utility of Follow-Up Echocardiograms in Uncomplicated PDA Device Closures Performed After Infancy.

Rachel Reo, Erin Van Pelt, Casey Lovelace, Anne Eshelman, Brian Beckman, Joanne Chisolm, Brian Boe, Carl Backes, Clifford L Cua

Open access · goldAbstract read
In one paragraph

Article in Cardiology and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Rachel ReoHeart Center, Nationwide Children's Hospital, Columbus, OH, USA.
Erin Van PeltHeart Center, Nationwide Children's Hospital, Columbus, OH, USA.
Casey LovelaceHeart Center, Nationwide Children's Hospital, Columbus, OH, USA.
Anne EshelmanHeart Center, Nationwide Children's Hospital, Columbus, OH, USA.
Brian BeckmanHeart Center, Nationwide Children's Hospital, Columbus, OH, USA.
Joanne ChisolmHeart Center, Nationwide Children's Hospital, Columbus, OH, USA.
Brian BoeHeart Center, Nationwide Children's Hospital, Columbus, OH, USA.
Carl BackesHeart Center, Nationwide Children's Hospital, Columbus, OH, USA.
Clifford L CuaHeart Center, Nationwide Children's Hospital, Columbus, OH, USA. clcua@hotmail.com.ORCID http://orcid.org/0000-0002-9172-3874
Nationwide Children's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGuidelines recommend lifelong follow-up with transthoracic echocardiograms (TTE) for patients who had a patent ductus arteriosus (PDA) device closure via catheterization. The goal of this study was to determine the utility of follow-up TTE in patients who underwent an uncomplicated PDA device closure after infancy.

methodsChart review was performed on patients who had a PDA closure ≥ 1 year of age between 1/1/2002 and 6/1/2020. Patients were excluded if they had other congenital heart disease, did not have a follow-up TTE ≥ 6 months after procedure, had a residual PDA or velocity > 2.0 m/s in the left pulmonary artery (LPA) or descending aorta (DAo) on the first TTE ≥ 6 months after device placement. Time points included the initial TTE after the procedure, first TTE ≥ 6 months after procedure, and the most recent TTE.

resultsA total of 189 patients met the study criteria. The median age and weight at initial procedure were 2.7 (1.0-64.7) years and 12.5 (3.4-69.2) kg. Most recent TTE was performed 2.0 (0.4-17.0) years after PDA closure. There were no significant differences in fractional shortening (36.4 ± 5.0% vs. 36.9 ± 5.6%) or LPA velocity (1.1 ± 0.4 m/s vs. 1.1 ± 0.4 m/s) from initial to most recent TTE, respectively. Left ventricular internal diastolic diameter Z-score significantly decreased (1.4 ± 1.8 vs. - 0.01 ± 1.2, p < 0.01) and DAo peak velocity significantly increased (1.2 ± 0.3 m/s vs. 1.3 ± 0.3 m/s, p = 0.02) from initial to most recent TTE, respectively. No patient died or underwent an intervention on the LPA or DAo for stenosis. Seventy-five patients had a total of 208 repeat TTE > 1 year after PDA procedure with no change in clinical management.

conclusionsIn patients who underwent an uncomplicated PDA closure after infancy, TTE parameters improved or stayed within normal limits on the most recent TTE. Repeat lifetime TTEs after 1-year post-device placement in this population may not necessarily be needed if there are no clinical concerns.

Indexed as

EchocardiogramPatent ductus arteriosusTransthoracic echocardiogram

Identifiers

PMID35780440
PMCPMC9381662
OpenAlexW4283788602

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.