ArticleAging clinical and experimental research2022
Trajectories of MMSE and MoCA scores across the healthy adult lifespan in the Italian population.
Article in Aging clinical and experimental research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 16 citations in OpenAlex.
- Early detection of cognitive impairment in the general population through a digital tool targeting the prospective memory. A pilot study.Annals of medicine · 2025Article
- Hearing Loss and Cognitive Function: An Analysis in Older Adults at the Beginning of the Auditory Rehabilitation Process.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- Article
- Is the MMSE enough for MCI? A narrative review of the usefulness of the MMSE.Frontiers in psychology · 2025Review
- A pilot study investigating the effectiveness, appreciation, and feasibility of a cognitive stimulation program in dementia patients: online versus face-to-face.Frontiers in psychology · 2025Article
- Aging Processes of Working Memory in Different Modalities.Neurology international · 2024Article
- Combining Mini-Mental State Examination and Montreal Cognitive Assessment for assessing the clinical efficacy of cholinesterase inhibitors in mild Alzheimer's disease: a pilot study.Aging clinical and experimental research · 2024Article
- Comparing the Efficacy of Two Cognitive Screening Tools in Identifying Gray and White Matter Brain Damage among Older Adults.Journal of aging research · 2024Article
- Voxel-based morphometry of grey matter structures in Parkinson's Disease with wearing-off.Brain imaging and behavior · 2023Article
- Assessing cognitive decline in the aging brain: lessons from rodent and human studies.npj aging · 2023Review
- Sociodemographic features associated with the MoCA, SPPB, and GDS scores in a community-dwelling elderly population.BMC geriatrics · 2023Article
- The impact ofAlzheimer's & dementia (Amsterdam, Netherlands)Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study compares the performance at the Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA) across the healthy adult lifespan in an Italian population sample.
methodsThe MMSE and MoCA were administered to 407 Italian healthy native-speakers (165 males; age range 20-93 years; education range 4-25 years). A generalized Negative Binomial mixed model was run to profile MMSE and MoCA scores across 8 different age classes (≤ 30; 31-40; 41-50; 51-60; 61-70; 71-80; 81-85; ≥ 86) net of education and sex.
resultsMMSE and MoCA total scores declined with age (p < 0.001), with the MoCA proving to be "more difficult" than the MMSE (p < 0.001). The Age*Test interaction (p < 0.001) indicates that the MoCA proved to profile a sufficiently linear involutional trend in cognition with advancing age and to be able to detect poorer cognitive performances in individuals aged ≥ 71 years. By contrast, MMSE scores failed in capturing the expected age-related trajectory, reaching a plateau in the aforementioned age classes. DISCUSSION: The MoCA seems to be more sensitive than the MMSE in detecting age-related physiological decline of cognitive functioning across the healthy adult lifespan. The MoCA might be therefore more useful than the MMSE as a test for general cognitive screening aims.
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