Evidence map›Paper›PMID 35780184›Full record

ArticleEuropean journal of medical research2022

Biopsies of osseous jaw lesions using 3D-printed surgical guides: a clinical study.

Lukas Postl, Thomas Mücke, Stefan Hunger, Sabina Noreen Wuersching, Svenia Holberg, Oliver Bissinger, Rainer Burgkart, Michael Malek, Stefan Krennmair

Open access · goldAbstract read
In one paragraph

Article in European journal of medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Lukas PostlMedical Faculty, Johannes Kepler University Linz, Altenberger Strasse 69, 4040, Linz, Austria. lukasleo@gmx.at.ORCID http://orcid.org/0000-0001-8988-5746
Thomas MückeDepartment of Oral and Maxillo-Facial Surgery, Klinikum Rechts Der Isar, Technische Universitaet Muenchen, Munich, Germany.
Stefan HungerMedical Faculty, Johannes Kepler University Linz, Altenberger Strasse 69, 4040, Linz, Austria.
Sabina Noreen WuerschingDepartment of Conservative Dentistry and Periodontology, University Hospital, LMU Munich, Munich, Germany.
Svenia HolbergNumBioLab, Ludwig-Maximilians University of Munich, Munich, Germany.
Oliver BissingerDepartment of Oral and Maxillofacial Surgery, Medizinische Universitaet Innsbruck, Innsbruck, Austria.
Rainer BurgkartClinic of Orthopaedics and Sportorthopaedics, Klinikum Rechts Der Isar, Technische Universitaet Muenchen, Munich, Germany.
Michael MalekClinic of Oral and Maxillofacial Surgery, Kepler University Hospital, Johannes Kepler University, Linz, Austria.
Stefan KrennmairMedical Faculty, Johannes Kepler University Linz, Altenberger Strasse 69, 4040, Linz, Austria.
Johannes Kepler University of Linz · ATTUM Klinikum · DEInnsbruck Medical University · ATLMU Klinikum · DELudwig-Maximilians-Universität München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBone biopsies are often necessary to make a diagnosis in the case of irregular bone structures of the jaw. A 3D-printed surgical guide may be a helpful tool for enhancing the accuracy of the biopsy and for ensuring that the tissue of interest is precisely removed for examination. This study was conducted to compare the accuracy of biopsies performed with 3D-printed surgical guides to that of free-handed biopsies.

methodsComputed tomography scans were performed on patients with bony lesions of the lower jaw. Surgical guides were planned via computer-aided design and manufactured by a 3D-printer. Biopsies were performed with the surgical guides. Bone models of the lower jaw with geometries identical to the patients' lower jaws were produced using a 3D-printer. The jaw models were fitted into a phantom head model and free-handed biopsies were taken as controls. The accuracy of the biopsies was evaluated by comparing the parameters for the axis, angle and depth of the biopsies to the planned parameters.

resultsEight patients were included. The mean deviation between the biopsy axes was significantly lower in guided procedures than in free-handed biopsies (1.4 mm ± 0.9 mm; 3.6 mm ± 1.0 mm; p = 0.0005). The mean biopsy angle deviation was also significantly lower in guided biopsies than in free-handed biopsies (6.8° ± 4.0; 15.4° ± 3.6; p = 0.0005). The biopsy depth showed no significant difference between the guided and the free-handed biopsies.

conclusionsComputer-guided biopsies allow significantly higher accuracy than free-handed procedures.

Indexed as

HandMandibleBiopsy, Fine-NeedleHumansPrinting, Three-DimensionalTomography, X-Ray Computed3D-printed bone models3D-printed surgical guideBiopsyComputer-assisted surgeryComputer-guided surgeryStereolithography

Identifiers

PMID35780184
PMCPMC9250179
OpenAlexW4283776260

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.