Evidence map›Paper›PMID 35780136›Full record

GuidelineHarm reduction journal2022

Priority setting for Canadian Take-Home Naloxone best practice guideline development: an adapted online Delphi method.

Max Ferguson, Andrea Medley, Katherine Rittenbach, Thomas D Brothers, Carol Strike, Justin Ng, Pamela Leece, Tara Elton-Marshall, Farihah Ali, Diane L Lorenzetti and 1 more

Open access · goldAbstract readPractice Guideline
In one paragraph

Guideline in Harm reduction journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Ten Priorities for Research Addressing the Intersections of Brain Injury, Mental Health and Addictions: A Stakeholder-Driven Priority-Setting Study.Health expectations : an international journal of public participation in health care and health policy · 2024
    Article
  4. Article
  5. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Article
  6. Guidance on take-home naloxone distribution and use by community overdose responders in Canada.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 3 countries.

Max FergusonBC Centre for Disease Control, Vancouver, BC, Canada.
Andrea MedleyBloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
Katherine RittenbachAlberta Health Services (AHS), Edmonton, AB, Canada.
Thomas D BrothersDepartment of Medicine, Dalhousie University, Halifax, NS, Canada.
Carol StrikeDalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada.
Justin NgBC Centre for Disease Control, Vancouver, BC, Canada.
Pamela LeecePublic Health Ontario (PHO), Toronto, ON, Canada.
Tara Elton-MarshallSchool of Epidemiology and Public Health, University of Ottawa, Ottawa, ON, Canada.
Farihah AliCentre for Addiction and Mental Health, Institute of Mental Health Policy Research, Toronto, ON, Canada.
Diane L LorenzettiUniversity of Calgary, Calgary, AB, Canada.
Jane A BuxtonBC Centre for Disease Control, Vancouver, BC, Canada. jane.buxton@bccdc.ca.
BC Centre for Disease Control · CAUniversity of Calgary · CACentre for Addiction and Mental Health · CAJohns Hopkins University · USPublic Health Ontario · CAUniversity College London · GBUniversity of British Columbia · CAUniversity of Ottawa · CAUniversity of Toronto · CA

Funding

Advancing Clinical Research Training within Addiction Residency ProgramsR25DA033211 · NIDA · BOSTON MEDICAL CENTER · PI Patrick O'Connor, JEFFREY H. SAMET · 2012 to 2026
$4.2M
CIHR CIHR-FRN# 171259CIHR OCC-154821NIDA NIH HHS R25 DA033211
6 · The paper itself

Abstract

backgroundTake-Home Naloxone (THN) is a core intervention aimed at addressing the toxic illicit opioid drug supply crisis. Although THN programs are available in all provinces and territories throughout Canada, there are currently no standardized guidelines for THN programs. The Delphi method is a tool for consensus building often used in policy development that allows for engagement of stakeholders.

methodsWe used an adapted anonymous online Delphi method to elicit priorities for a Canadian guideline on THN as a means of facilitating meaningful stakeholder engagement. A guideline development group generated a series of key questions that were then brought to a 15-member voting panel. The voting panel was comprised of people with lived and living experience of substance use, academics specializing in harm reduction, and clinicians and public health professionals from across Canada. Two rounds of voting were undertaken to score questions on importance for inclusion in the guideline.

resultsNine questions that were identified as most important include what equipment should be in THN kits, whether there are important differences between intramuscular and intranasal naloxone administration, how stigma impacts access to distribution programs, how effective THN programs are at saving lives, what distribution models are most effective and equitable, storage considerations for naloxone in a community setting, the role of CPR and rescue breathing in overdose response, client preference of naloxone distribution program type, and what aftercare should be provided for people who respond to overdoses.

conclusionsThe Delphi method is an equitable consensus building process that generated priorities to guide guideline development.

Indexed as

Drug OverdoseIllicit DrugsNaloxoneNarcotic AntagonistsCanadaDelphi TechniqueHumansIllicit DrugsNaloxoneNarcotic AntagonistsDelphiHarm reductionNaloxone

Identifiers

PMID35780136
PMCPMC9250272
OpenAlexW4283776772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.