Evidence map›Paper›PMID 35780073›Full record

ArticleEuropean journal of internal medicine2022

Participants' informed consent in adaptive, platform drug trials in hospitalized COVID-19 patients: Not all approaches are ethically acceptable.

Rafael Dal-Ré, Arthur L Caplan, Teck Chuan Voo

Open access · greenAbstract read
In one paragraph

Article in European journal of internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Rafael Dal-RéEpidemiology Unit, Health Research Institute-Fundación Jiménez Díaz University Hospital, Universidad Autónoma de Madrid, Avda. Reyes Católicos 2, Madrid E-28040, Spain. Electronic address: rafael.dalre@quironsalud.es.
Arthur L CaplanDivision of Medical Ethics, Grossman School of Medicine, NYU Langone Medical Center, 550 1st Ave., New York, NY 10016, USA.
Teck Chuan VooCentre for Biomedical Ethics, Yong Loo Lin School of Medicine, Clinical research Centre, National University of Singapore, 21 Lower Kent Ridge Rd 117597, Block MD11, #02-03, 10 Medical Drive, Singapore 119077, Singapore.
Hospital Universitario Fundación Jiménez Díaz · ESNational University of Singapore · SGNYU Langone Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19Adaptive Clinical Trials as TopicHumansInformed ConsentSARS-CoV-2Adaptive randomized controlled trialsCOVID-19EthicsI-SPY COVID trialMedicinesPost-randomization informed consent

Identifiers

PMID35780073
PMCPMC9236980
OpenAlexW4283662059

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.