Evidence map›Paper›PMID 35779442›Full record

ArticleRedox biology2022

The m6A reader YTHDF3-mediated PRDX3 translation alleviates liver fibrosis.

Ruimin Sun, Xinyao Tian, Yang Li, Yan Zhao, Zhecheng Wang, Yan Hu, Lijun Zhang, Yue Wang, Dongyan Gao, Shusen Zheng and 1 more

Open access · goldAbstract read
In one paragraph

Article in Redox biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 86 citations in OpenAlex.

  1. The Role of NMedComm · 2026
    Review
  2. METTL3 inhibition attenuates AFBJournal of animal science and biotechnology · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. METTL14-mediated mEpigenetics · 2025
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Ruimin SunDepartment of Pharmacology, Dalian Medical University, Dalian, China; Institute of Integrative Medicine, Dalian Medical University, Dalian, China.
Xinyao TianDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Department of Hepatobiliary and Pancreatic Surgery, Department of Liver Transplantation, Shulan (Hangzhou) Hospital, Hangzhou, China.
Yang LiDepartment of Gastrointestinal Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Yan ZhaoDepartment of Pharmacology, Dalian Medical University, Dalian, China.
Zhecheng WangDepartment of Pharmacology, Dalian Medical University, Dalian, China.
Yan HuDepartment of Pharmacology, Dalian Medical University, Dalian, China.
Lijun ZhangDepartment of Pharmacology, Dalian Medical University, Dalian, China.
Yue WangDepartment of Pharmacology, Dalian Medical University, Dalian, China.
Dongyan GaoDepartment of Pharmacology, Dalian Medical University, Dalian, China.
Shusen ZhengDivision of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China; Department of Hepatobiliary and Pancreatic Surgery, Department of Liver Transplantation, Shulan (Hangzhou) Hospital, Hangzhou, China. Electronic address: shusenzheng@zju.edu.cn.
Jihong YaoDepartment of Pharmacology, Dalian Medical University, Dalian, China. Electronic address: yaojihong65@hotmail.com.
Dalian Medical University · CNFirst Affiliated Hospital Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peroxiredoxin 3 (PRDX3) acts as a master regulator of mitochondrial oxidative stress and exerts hepatoprotective effects, but the role of PRDX3 in liver fibrosis is not well understood. N

Indexed as

Hepatic Stellate CellsLiver CirrhosisPeroxiredoxin IIIRNA-Binding ProteinsAnimalsLiverMicePeroxiredoxinsRNA, MessengerPeroxiredoxin IIIPeroxiredoxinsPrdx3 protein, mouseRNA-Binding ProteinsRNA, Messenger

Identifiers

PMID35779442
PMCPMC9287738
OpenAlexW4283462606

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.