Evidence map›Paper›PMID 35779272›Full record

ArticleJournal of clinical ultrasound : JCU2022

Differential diagnosis of diffuse sclerotic thyroid papillary carcinoma and Hashimoto's thyroiditis using fine-needle aspiration cytology, BRAF

Xian Wang, Feiju Xu, Juan Gao, Enock Adjei Agyekum, Hui Sun, Guoliang Zhang, Xinxin Li, Hong Xiang, Shudong Hu, Xiaoqin Qian

Open access · hybridAbstract read
In one paragraph

Article in Journal of clinical ultrasound : JCU, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Xian WangDepartment of Ultrasound, Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.ORCID https://orcid.org/0000-0002-5950-2545
Feiju XuDepartment of Ultrasound, Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Juan GaoDepartment of Ultrasound, Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.ORCID https://orcid.org/0000-0002-0650-8759
Enock Adjei AgyekumSchool of Medicine, Jiangsu University, Zhenjiang, China.ORCID https://orcid.org/0000-0003-0021-8555
Hui SunDepartment of Pathology, Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Guoliang ZhangDepartment of General Surgery, Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Xinxin LiDepartment of Otolaryngology head and Neck Surgery, Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Hong XiangDepartment of Pediatric, Affiliated Hospital of Jiangsu University, Zhenjiang, China.
Shudong HuDepartment of Radiology, Affiliated Hospital, Jiangnan University, Wuxi, China.
Xiaoqin QianDepartment of Ultrasound, Affiliated People's Hospital of Jiangsu University, Zhenjiang, China.
Jiangsu University · CNJiangnan University · CN

Funding

Clinical Medicine ScienceJiangsu Provincial Health Commission Z2021071Zhenjiang Commission of Science and Technology SH2020046
6 · The paper itself

Abstract

backgroundThe diffuse sclerosing variant of papillary thyroid carcinoma (DSV-PTC) has ultrasound findings that are similar to Hashimoto's thyroiditis (HT), resulting in under-diagnosis. DSV-PTC combined with HT is also common, so early and accurate diagnosis of DSV-PTC using a variety of diagnostic techniques, including FNAC, BRAF

objectiveTo assess the diagnostic value of fine-needle aspiration cytology (FNAC) and BRAF

methodsWe performed a retrospective analysis of 40 patients with pathologically confirmed DSV-PTC and 43 patients with HT admitted to our hospital's ultrasound department between January 2015 and December 2020. Preoperative FNAC, BRAF

resultsThe mean elastic strain rate ratio (E1/E2) of the 40 DSV-PTC cases was 5.75 ± 2.14, while that of the 43 HT cases was 2.81 ± 1.20. The receiver operating characteristic (ROC) curve was generated using the average value of E2/E1. The area under the ROC curve was 0.910, and the optimal E2/E1 cut-off value was 4.500. When FNAC, BRAF

conclusionsThe use of FNAC, BRAF

Indexed as

Carcinoma, PapillaryElasticity Imaging TechniquesHashimoto DiseaseThyroid NeoplasmsBiopsy, Fine-NeedleDiagnosis, DifferentialHumansMutationProto-Oncogene Proteins B-rafRetrospective StudiesSensitivity and SpecificityThyroid Cancer, PapillaryBRAF protein, humanProto-Oncogene Proteins B-rafBRAFV600Ediffuse sclerosing variantelastic strain rateFNACpapillary thyroid carcinomaultrasound

Identifiers

PMID35779272
PMCPMC9541506
OpenAlexW4283772735

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.