SynthesisEuropean archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry2022
Chemotherapy-induced oral mucositis in children and adolescents: a systematic review.
Synthesis in European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07073092 (Propolis for Management of Chemotherapy-Induced Oral Mucositis in Pediatric Patients), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Propolis for Management of Chemotherapy-Induced Oral Mucositis in Pediatric Patients: A Randomized Controlled Clinical Trial With Biochemical Analysis
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.
- Prevention and Treatment of Oral Mucositis in Pediatric Patients: Systematic Review and Meta-Analysis of Randomized Controlled Trials.In vivo (Athens, Greece)Pooled it
- Treatment Approaches for Therapy-Associated Mucosal Lesions in Pediatric Oncohematology Patients: Findings from a Retrospective Observational Study in an Italian Pediatric Hospital.Healthcare (Basel, Switzerland) · 2026Article
- The parents voice on oral health care from two paediatric oncology units.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2026Observational
- Article
- Dental caries in childhood cancer survivors.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Use of topical Vitamin E in oral mucositis in patients undergoing oncology treatment. Scoping review.Medicina oral, patologia oral y cirugia bucal · 2026Article
- Polyphenolic nanodot-integrated spindle nanoplatform heals oral mucositis via microbiota restoration and glycolysis inhibition.Journal of nanobiotechnology · 2026Article
- Knowledge, attitudes, and practices of family members of children undergoing chemoradiotherapy regarding oral mucositis.Asia-Pacific journal of oncology nursing · 2025Article
- Risk Factors for Oral Mucositis in Pediatric Oncology Patients Undergoing Chemotherapy: A Prospective Cohort.Asian Pacific journal of cancer prevention : APJCP · 2025Article
- Article
- Causes and management of acute oncological pain: a narrative review.Anaesthesia · 2025Review
- Chemotherapy-induced oral mucositis: hierarchical analysis of recurrence factors.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2024Article
- Review
- Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe present systematic review aims to describe the incidence and severity of chemotherapy-related oral mucositis in children and adolescents affected by hematologic and solid tumors.
methodsAn electronic search was performed on PubMed, Scopus, Web of Science, Cochrane Library, and EBSCO up to the 8th November 2020. The PRISMA protocol was followed for the article selection and inclusion. The risk of bias in individual studies was evaluated through the Newcastle-Ottawa Scale. Data were summarized using mean and standard deviation for continuous variables, while categorical ones were described with frequency and percentage.
resultsA number of 9940 records were obtained after the electronic search. Seventeen of them were included in the qualitative analysis after the two stages of screening, while none of these articles was considered eligible for the quantitative analysis. The mean incidence of oral mucositis was 53.6% and it ranged from 16.7 to 91.5%, while severe oral mucositis accounted for the 15.8% (0.0-35.2%) among selected studies. Most of the articles included both patients with solid and hematologic tumors, while only five of them described oral mucositis in children with acute lymphoblastic leukemia. Even the kinds of chemotherapy administered were extremely variable.
conclusionIn conclusion, about half of the patients submitted to cancer chemotherapy developed oral mucositis with an incidence and severity that varies depending on the primary disease and the kind of drugs administered.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.