Evidence map›Paper›PMID 35779158›Full record

ArticleInternational urology and nephrology2022

Seasonal pattern in elderly hospitalized with acute kidney injury: a retrospective nationwide study in Italy.

Alfredo De Giorgi, Alda Storari, Pedro Manuel Rodríguez-Muñoz, Rosaria Cappadona, Nicola Lamberti, Fabio Manfredini, Pablo Jesús López-Soto, Roberto Manfredini, Fabio Fabbian

Abstract read
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Article in International urology and nephrology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alfredo De GiorgiClinica Medica Unit, University Hospital of Ferrara, Ferrara, Italy.
Alda StorariNephrology and Dialysis Unit, University Hospital of Ferrara, Ferrara, Italy.
Pedro Manuel Rodríguez-MuñozDepartment of Nursing and Physiotherapy, Universidad de Salamanca, Salamanca, Spain.ORCID http://orcid.org/0000-0002-7933-952X
Rosaria CappadonaDepartment of Medical Science, University of Ferrara, Via Luigi Borsari 46, 44121, Ferrara, Italy.ORCID http://orcid.org/0000-0003-3254-6043
Nicola LambertiDepartment of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy.ORCID http://orcid.org/0000-0001-5763-3069
Fabio ManfrediniDepartment of Neuroscience and Rehabilitation, University of Ferrara, Ferrara, Italy.ORCID http://orcid.org/0000-0001-9476-6434
Pablo Jesús López-SotoDepartment of Nursing, Instituto Maimónides de Investigación Biomédica de Córdoba, Córdoba, Spain.ORCID http://orcid.org/0000-0002-1046-6686
Roberto ManfrediniDepartment of Medical Science, University of Ferrara, Via Luigi Borsari 46, 44121, Ferrara, Italy.ORCID http://orcid.org/0000-0002-8364-2601
Fabio FabbianDepartment of Medical Science, University of Ferrara, Via Luigi Borsari 46, 44121, Ferrara, Italy. f.fabbian@ospfe.it.ORCID http://orcid.org/0000-0001-5189-3695

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAcute kidney injury (AKI) frequently complicates hospitalization and is associated with in-hospital mortality (IHM). It has been reported a seasonal trend in different clinical conditions. The aim of this study was to evaluate the possible relationship between seasons of the year and IHM in elderly hospitalized patients with AKI.

methodsWe selected all admissions complicated by AKI between 2000 and 2015 recorded in the Italian National Hospital Database. ICD-9-CM code 584.xx identified subjects with age ≥ 65 years and age, sex, comorbidity burden, need of dialysis treatment and IHM were compared in hospitalizations recorded during the four seasons. Moreover, we plotted the AKI observed/expected ratio and percentage of mortality during the study period.

resultsWe evaluated 759,720 AKI hospitalizations (mean age 80.5 ± 7.8 years, 52.2% males). Patients hospitalized with AKI during winter months had higher age, prevalence of dialysis-dependent AKI, and number of deceased patients. In whole population IHM was higher in winter and lower in summer, while the AKI observed/expected ratio demonstrated two peaks, one in summer and one in winter. Logistic regression analysis demonstrated that parameters such as age, autumn, winter, comorbidity burden were positively associated with IHM.

conclusionWe conclude that a seasonality exists in AKI, however, relationship between seasons and AKI could vary depending on the aspects considered. Both autumn and winter months are independent risk factors for IHM in patients with AKI regardless of age, sex and comorbidity burden. On the contrary, summer time reduces the risk of death during hospitalizations with AKI.

Indexed as

Acute Kidney InjuryHospitalizationAgedAged, 80 and overFemaleHospital MortalityHumansMaleRetrospective StudiesRisk FactorsSeasonsAcute kidney injuryChronobiology phenomenaComorbidityElderlyIn-hospital mortalitySeasons

Identifiers

PMID35779158
PMCPMC9605924

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.