Evidence map›Paper›PMID 35779082›Full record

Trial reportEuropean journal of nuclear medicine and molecular imaging2022

A first-in-human study of [

Ivan Ho Shon, Thomas Hennessy, Jennifer Guille, Michael P Gotsbacher, Angelina J Lay, Bruce McBride, Rachel Codd, Philip J Hogg

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in European journal of nuclear medicine and molecular imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Preparation of a Dithiol-Reactive Probe for PET Imaging of Cell Death.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ivan Ho ShonDepartment of Nuclear Medicine and PET, Prince of Wales Hospital, Sydney, Australia. i.hoshon@unsw.edu.au.ORCID 0000-0002-2036-8190
Thomas HennessyDepartment of Nuclear Medicine and PET, Prince of Wales Hospital, Sydney, Australia.
Jennifer GuilleDepartment of Nuclear Medicine and PET, Prince of Wales Hospital, Sydney, Australia.
Michael P GotsbacherSchool of Medical Sciences, University of Sydney, Sydney, Australia.ORCID 0000-0002-7153-1250
Angelina J LayThe Centenary Institute, University of Sydney, Sydney, Australia.
Bruce McBrideDepartment of Nuclear Medicine and PET, Prince of Wales Hospital, Sydney, Australia.
Rachel CoddSchool of Medical Sciences, University of Sydney, Sydney, Australia.ORCID 0000-0002-2703-883X
Philip J HoggThe Centenary Institute, University of Sydney, Sydney, Australia.ORCID 0000-0001-6486-2863
The University of Sydney · AUPrince of Wales Hospital · AUCentenary Institute · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study assesses human biodistribution, radiation dosimetry, safety and tumour uptake of cell death indicator labelled with

methodsFive participants with at least one extracranial site of solid malignancy > 2 cm and no active cancer treatment in the 8 weeks prior to the study were enrolled. Participants were administered 205 ± 4.1 MBq (range, 200-211 MBq) of [

results[

conclusion[

trial registrationACTRN12621000641897 (28/5/2021, retrospectively registered).

Indexed as

NeoplasmsRadiopharmaceuticalsCell DeathDNA NucleotidylexotransferaseElectronsGallium RadioisotopesHumansPositron-Emission TomographyPositron Emission Tomography Computed TomographyRadiometryTissue DistributionDNA NucleotidylexotransferaseGallium RadioisotopesRadiopharmaceuticalsApoptosisCell deathGallium-68NecrosisPositron emission tomographyPositron emission tomography computed tomography

Identifiers

PMID35779082
PMCPMC9525422
OpenAlexW4283768665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.