ArticleRadiation oncology (London, England)2022
Single-isocenter multiple-target stereotactic radiosurgery for multiple brain metastases: dosimetric evaluation of two automated treatment planning systems.
Article in Radiation oncology (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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Who cites it
28 citing papers in PubMed.
- Memory circuit dosimetry in patients with brain metastases treated with Sparing Memory with Advanced Radiosurgery Targeting (SMART) technique.Clinical and translational radiation oncology · 2026Article
- Evaluation of EPID-Based Transmission and DLG Correction Methods for Dosimetric Verification in HyperArc Single-Isocenter Multiple Target Radiosurgery.Diagnostics (Basel, Switzerland) · 2026Article
- Effects of intrafractional motion on targeting accuracy in frameless single-isocenter multi-target stereotactic radiosurgery.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2026Article
- Impact of Tumor Geometry on Dose Distribution and Delivery Accuracy in Multi-Target Stereotactic Radiosurgery.Brain sciences · 2026Article
- A multi-institutional EPID-based 3D dose reconstruction model in a virtual phantom for standardized patient QA, benchmarking and auditing for stereotactic radiosurgery.Physics and imaging in radiation oncology · 2026Article
- Article
- Neurofilament light and glial fibrillary acidic protein do not reflect neuronal or glial damage during different intracranial radiotherapy regimes: a pilot study.Frontiers in oncology · 2026Article
- Dual optimization in single-isocenter radiosurgery for multiple brain metastases: a dosimetric planning study.Frontiers in oncology · 2026Article
- Paradigm shift in patients with multiple brain metastases from whole brain radiotherapy to high precision multimodality treatment including stereotactic radiotherapy.Journal of neuro-oncology · 2025Article
- Quality and Dosimetric Accuracy of Linac-Based Single-Isocenter Treatment Plans for Four to Eighteen Brain Metastases.Cancers · 2025Article
- Impact of two-dimensional dosimetric leaf gap on SRS-VMAT for single-isocenter multi-target brain metastases.Scientific reports · 2025Article
- Article
- New Approaches in Radiotherapy.Cancers · 2025Review
- T-DM1 with concurrent radiotherapy in HER2-positive breast cancer: preclinical evaluation and mechanisms, prediction, and exploration of adverse effects.Discover oncology · 2025Review
- Dosimetric and radiobiological evaluation of stereotactic radiosurgery using volumetric modulated arc therapy and dynamic conformal arc therapy for multiple brain metastases.Scientific reports · 2025Article
- Spatial accuracy of dose delivery significantly impacts the planning target volume margin in linear accelerator-based intracranial stereotactic radiosurgery.Scientific reports · 2025Article
- Effect of different optimization parameters in single isocenter multiple brain metastases radiosurgery.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2024Article
- Exploring feasibility criteria for stereotactic radiosurgical treatment of multiple brain metastases using five linac machines.Journal of applied clinical medical physics · 2024Article
- Improving the Efficiency of Single-Isocenter Multiple Metastases Stereotactic Radiosurgery Treatment.Advances in radiation oncology · 2024Article
- Assessing the sensitivity and suitability of a range of detectors for SIMT PSQA.Journal of applied clinical medical physics · 2024Article
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Authors and funding
6 authors.
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Abstract
purposeAutomated treatment planning systems are available for linear accelerator (linac)-based single-isocenter multi-target (SIMT) stereotactic radiosurgery (SRS) of brain metastases. In this study, we compared plan quality between Brainlab Elements Multiple Brain Metastases (Elements MBM) software which utilizes dynamic conformal arc therapy (DCAT) and Varian HyperArc (HA) software using a volumetric modulated arc therapy (VMAT) technique. PATIENTS AND
methodsBetween July 2018 and April 2021, 36 consecutive patients ≥ 18 years old with 367 metastases who received SIMT SRS at UPMC Hillman Cancer San Pietro Hospital, Rome, were retrospectively evaluated. SRS plans were created using the commercial software Elements MBM SRS (Version 1.5 and 2.0). Median cumulative gross tumor volume (GTV) and planning tumor volume (PTV) were 1.33 cm
resultsBoth techniques resulted in high-quality treatment plans, although Element MBM DCAT plans performed significantly better than HA VMAT plans, especially in cases of more than 10 lesions). Median V
conclusionsBoth Elements MBM and HA systems were able to generate high-quality plans in patients with up to 25 brain metastases. DCAT plans performed better in terms of normal brain sparing, especially in patients with more than ten lesions and limited total tumor volume.
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