Evidence map›Paper›PMID 35778615›Full record

ArticleScientific reports2022

Automated image curation in diabetic retinopathy screening using deep learning.

Paul Nderitu, Joan M Nunez do Rio, Ms Laura Webster, Samantha S Mann, David Hopkins, M Jorge Cardoso, Marc Modat, Christos Bergeles, Timothy L Jackson

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. On the Analyses of Medical Images Using Traditional Machine Learning Techniques and Convolutional Neural Networks.Archives of computational methods in engineering : state of the art reviews · 2023
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Paul NderituSection of Ophthalmology, King's College London, London, UK. p.nderitu@doctors.org.uk.
Joan M Nunez do RioSection of Ophthalmology, King's College London, London, UK.
Ms Laura WebsterSouth East London Diabetic Eye Screening Programme, Guy's and St Thomas' Foundation Trust, London, UK.
Samantha S MannSouth East London Diabetic Eye Screening Programme, Guy's and St Thomas' Foundation Trust, London, UK.
David HopkinsDepartment of Diabetes, School of Life Course Sciences, King's College London, London, UK.
M Jorge CardosoSchool of Biomedical Engineering & Imaging Sciences, King's College London, London, UK.
Marc ModatSchool of Biomedical Engineering & Imaging Sciences, King's College London, London, UK.
Christos BergelesSchool of Biomedical Engineering & Imaging Sciences, King's College London, London, UK.
Timothy L JacksonSection of Ophthalmology, King's College London, London, UK.

Funding

Diabetes UK 20/0006144
6 · The paper itself

Abstract

Diabetic retinopathy (DR) screening images are heterogeneous and contain undesirable non-retinal, incorrect field and ungradable samples which require curation, a laborious task to perform manually. We developed and validated single and multi-output laterality, retinal presence, retinal field and gradability classification deep learning (DL) models for automated curation. The internal dataset comprised of 7743 images from DR screening (UK) with 1479 external test images (Portugal and Paraguay). Internal vs external multi-output laterality AUROC were right (0.994 vs 0.905), left (0.994 vs 0.911) and unidentifiable (0.996 vs 0.680). Retinal presence AUROC were (1.000 vs 1.000). Retinal field AUROC were macula (0.994 vs 0.955), nasal (0.995 vs 0.962) and other retinal field (0.997 vs 0.944). Gradability AUROC were (0.985 vs 0.918). DL effectively detects laterality, retinal presence, retinal field and gradability of DR screening images with generalisation between centres and populations. DL models could be used for automated image curation within DR screening.

Indexed as

Deep LearningDiabetes MellitusDiabetic RetinopathyMacula LuteaHumansMass ScreeningRetina

Identifiers

PMID35778615
PMCPMC9249740

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.