Evidence map›Paper›PMID 35778564›Full record

ReviewNature chemistry2022

Chemical fuels for molecular machinery.

Stefan Borsley, David A Leigh, Benjamin M W Roberts

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Recent Advancements in Information Ratchet Design.Molecules (Basel, Switzerland) · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Hybrid Inorganic-Organic Rotaxanes and Related Compounds.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  13. Terrestrial locomotion of microscopic robots enabled by 3D nanomembranes with nonreciprocal shape morphing.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  14. Article
  15. Catalysis-driven Active Transport Across a Liquid Membrane.Angewandte Chemie (International ed. in English) · 2025
    Article
  16. A Catalysis-Driven Dual Molecular Motor.Journal of the American Chemical Society · 2025
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Stefan Borsley *Department of Chemistry, University of Manchester, Manchester, UK.ORCID http://orcid.org/0000-0001-9637-4178
David A LeighDepartment of Chemistry, University of Manchester, Manchester, UK. david.leigh@manchester.ac.uk.ORCID http://orcid.org/0000-0002-1202-4507
Benjamin M W Roberts *Department of Chemistry, University of Manchester, Manchester, UK.ORCID http://orcid.org/0000-0003-2820-8359

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemical reaction networks that transform out-of-equilibrium 'fuel' to 'waste' are the engines that power the biomolecular machinery of the cell. Inspired by such systems, autonomous artificial molecular machinery is being developed that functions by catalysing the decomposition of chemical fuels, exploiting kinetic asymmetry to harness energy released from the fuel-to-waste reaction to drive non-equilibrium structures and dynamics. Different aspects of chemical fuels profoundly influence their ability to power molecular machines. Here we consider the structure and properties of the fuels that biology has evolved and compare their features with those of the rudimentary synthetic chemical fuels that have so far been used to drive autonomous non-equilibrium molecular-level dynamics. We identify desirable, but context-specific, traits for chemical fuels together with challenges and opportunities for the design and invention of new chemical fuels to power synthetic molecular machinery and other dissipative nanoscale processes.

Indexed as

CatalysisKinetics

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.