Evidence map›Paper›PMID 35778476›Full record

ArticleScientific reports2022

RF-CNN-F: random forest with convolutional neural network features for coronary artery disease diagnosis based on cardiac magnetic resonance.

Fahime Khozeimeh, Danial Sharifrazi, Navid Hoseini Izadi, Javad Hassannataj Joloudari, Afshin Shoeibi, Roohallah Alizadehsani, Mehrzad Tartibi, Sadiq Hussain, Zahra Alizadeh Sani, Marjane Khodatars and 6 more

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Automated vertigo diagnosis using video-oculography and artificial intelligence for clinic-based triage: Preliminary results.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
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  5. Uncover This Tech Term: Random Forest.Korean journal of radiology · 2025
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  10. Artificial Intelligence in Coronary Artery Interventions: Preprocedural Planning and Procedural Assistance.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Review
  11. Article
  12. A systematic review of machine learning in heart disease prediction.Turkish journal of biology = Turk biyoloji dergisi · 2025
    Review
  13. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Fahime KhozeimehInstitute for Intelligent Systems Research and Innovation (IISRI), Deakin University, Geelong, Australia.
Danial SharifraziDepartment of Computer Engineering, School of Technical and Engineering, Shiraz Branch, Islamic Azad University, Shiraz, Iran.
Navid Hoseini IzadiDepartment of Electrical and Computer Engineering, Isfahan University of Technology, Isfahan, 84156-83111, Iran.
Javad Hassannataj JoloudariDepartment of Computer Engineering, Faculty of Engineering, University of Birjand, Birjand, Iran.
Afshin ShoeibiFPGA Laboratory, Faculty of Electrical Engineering, K. N. Toosi University of Technology, Tehran, Islamic Republic of Iran.
Roohallah AlizadehsaniInstitute for Intelligent Systems Research and Innovation (IISRI), Deakin University, Geelong, Australia. r.alizadehsani@deakin.edu.au.
Mehrzad TartibiDelbeat Inc., Berkeley, CA, USA.
Sadiq HussainDibrugarh University, Assam, 786004, India.
Zahra Alizadeh SaniOmid Hospital, Iran University of Medical Sciences, Tehran, Iran.
Marjane KhodatarsDepartment of Medical Engineering, Mashhad Branch, Islamic Azad University, Mashhad, Iran.
Delaram SadeghiDepartment of Medical Engineering, Mashhad Branch, Islamic Azad University, Mashhad, Iran.
Abbas KhosraviInstitute for Intelligent Systems Research and Innovation (IISRI), Deakin University, Geelong, Australia.
Saeid NahavandiInstitute for Intelligent Systems Research and Innovation (IISRI), Deakin University, Geelong, Australia.
Ru-San TanDepartment of Cardiology, National Heart Centre Singapore, Singapore, Singapore.
U Rajendra AcharyaDepartment of Electronics and Computer Engineering, Ngee Ann Polytechnic, Singapore, Singapore.
Sheikh Mohammed Shariful IslamSchool of Exercise and Nutrition Sciences, Institute for Physical Activity and Nutrition, Deakin University, Geelong, VIC, 3220, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary artery disease (CAD) is a prevalent disease with high morbidity and mortality rates. Invasive coronary angiography is the reference standard for diagnosing CAD but is costly and associated with risks. Noninvasive imaging like cardiac magnetic resonance (CMR) facilitates CAD assessment and can serve as a gatekeeper to downstream invasive testing. Machine learning methods are increasingly applied for automated interpretation of imaging and other clinical results for medical diagnosis. In this study, we proposed a novel CAD detection method based on CMR images by utilizing the feature extraction ability of deep neural networks and combining the features with the aid of a random forest for the very first time. It is necessary to convert image data to numeric features so that they can be used in the nodes of the decision trees. To this end, the predictions of multiple stand-alone convolutional neural networks (CNNs) were considered as input features for the decision trees. The capability of CNNs in representing image data renders our method a generic classification approach applicable to any image dataset. We named our method RF-CNN-F, which stands for Random Forest with CNN Features. We conducted experiments on a large CMR dataset that we have collected and made publicly accessible. Our method achieved excellent accuracy (99.18%) using Adam optimizer compared to a stand-alone CNN trained using fivefold cross validation (93.92%) tested on the same dataset.

Indexed as

Coronary Artery DiseaseHumansMachine LearningMagnetic Resonance ImagingMagnetic Resonance SpectroscopyNeural Networks, Computer

Identifiers

PMID35778476
PMCPMC9249743

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.