ArticleScientific reports2022
Characteristics and mortality of 561,379 hospitalized COVID-19 patients in Germany until December 2021 based on real-life data.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 47 citations in OpenAlex.
- Lessons Learned from Model-based Economic Evaluations of COVID-19 Drug Treatments Under Pandemic Circumstances: Results from a Systematic Review.PharmacoEconomics · 2024Pooled it
- Chronic Anticoagulation in Patients with Atrial Fibrillation and COVID-19: A Systematic Review and Meta-Analysis.Arquivos brasileiros de cardiologia · 2024Pooled it
- Nationwide trends in incidence and in-hospital mortality of ARDS in Germany, 2008-2022.Scientific reports · 2026Article
- Transfusion Practice in Elderly Surgical Patients in Germany-A Secondary Data Analysis of over 21 Million Patients over a Decade.Medicina (Kaunas, Lithuania) · 2026Article
- Temporal Urinary Metabolomic Profiling in ICU Patients with Critical COVID-19: A Pilot Study Providing Insights into Prognostic Biomarkers viaCurrent issues in molecular biology · 2026Article
- Critical risks of haemoadsorption for COVID-19 patients and directions for future evaluations: a nationwide propensity score matched cohort study.Scientific reports · 2025Observational
- Cost-effectiveness Analysis of Nirmatrelvir/Ritonavir for COVID-19 Among Individuals at High Risk: A Modeling Study.Open forum infectious diseases · 2025Article
- Time-series metabolomic profiling of SARS-CoV-2 infection: Possible prognostic biomarkers in patients in the ICU by ¹H-NMR analysis.PloS one · 2025Article
- Article
- Polyuria in COVID-19 Patients Undergoing Extracorporeal Membrane Oxygenation.Journal of clinical medicine · 2024Article
- Mechanical ventilation as a major driver of COVID-19 hospitalization costs: a costing study in a German setting.Health economics review · 2024Article
- Long-term mortality of Dutch COVID-19 patients admitted to the intensive care medicine: a retrospective analysis from a national quality registry.Critical care science · 2024Article
- High-dose methylprednisolone pulse therapy during refractory COVID-19 acute respiratory distress syndrome: a retrospective observational study.BMC pulmonary medicine · 2023Observational
- Changes in the Proteome of Platelets from Patients with Critical Progression of COVID-19.Cells · 2023Article
- COVID-19 associated bacterial infections in intensive care unit: a case control study.Scientific reports · 2023Article
- Higher urea-to-albumin ratio is associated with mortality risk in critically ill COVID-19 patients.Clinical nutrition ESPEN · 2023Article
- Mortality predictive value of APACHE II Scores in COVID-19 patients in the intensive care unit: a cross-sectional study.Annals of medicine and surgery (2012) · 2023Article
- Anticoagulation strategy and safety in critically ill COVID-19 patients: a French retrospective multicentre study.Thrombosis journal · 2023Article
- Antibiotic Usage in the COVID-19 Intensive Care Unit of an Infectious Diseases Hospital from Nord-Eastern Romania.Medicina (Kaunas, Lithuania) · 2023Article
- Cellular and molecular features of COVID-19 associated ARDS: therapeutic relevance.Journal of inflammation (London, England) · 2023Review
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5 authors at 2 institutions in 1 country.
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Abstract
The ongoing SARS-CoV-2 pandemic is characterized by poor outcome and a high mortality especially in the older patient cohort. Up to this point there is a lack of data characterising COVID-19 patients in Germany admitted to intensive care (ICU) vs. non-ICU patients. German Reimbursement inpatient data covering the period in Germany from January 1st, 2020 to December 31th, 2021 were analyzed. 561,379 patients were hospitalized with COVID-19. 24.54% (n = 137,750) were admitted to ICU. Overall hospital mortality was 16.69% (n = 93,668) and 33.36% (n = 45,947) in the ICU group. 28.66% (n = 160,881) of all patients suffer from Cardiac arrhythmia and 17.98% (n = 100,926) developed renal failure. Obesity showed an odds-ratio ranging from 0.83 (0.79-0.87) for WHO grade I to 1.13 (1.08-1.19) for grade III. Mortality-rates peaked in April 2020 and January 2021 being 21.23% (n = 4539) and 22.99% (n = 15,724). A third peak was observed November and December 2021 (16.82%, n = 7173 and 16.54%, n = 9416). Hospitalized COVID-19 patient mortality in Germany is lower than previously shown in other studies. 24.54% of all patients had to be treated in the ICU with a mortality rate of 33.36%. Congestive heart failure was associated with a higher risk of death whereas low grade obesity might have a protective effect on patient survival. High admission numbers are accompanied by a higher mortality rate.
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