Evidence map›Paper›PMID 35776854›Full record

SynthesisColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2022

Patient choice in colorectal cancer treatment - A systematic review and narrative synthesis of attribute-based stated preference studies.

Mikolaj Kowal, Francesca Douglas, David Jayne, David Meads

Abstract readSystematic Review
In one paragraph

Synthesis in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Patient choice in colorectal cancer treatment - A systematic review and narrative synthesis of attribute-based stated preference studies.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2022
    Pooled it
  3. Article
  4. Article
  5. Socio-economic predictors and between-hospital variation in permanent stoma rates after segmental resection of colorectal cancer. A population-based register study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025
    Article
  6. Preferences for treatment outcomes in rectal cancer: A discrete choice experiment among patients and healthy volunteers.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mikolaj KowalThe John Goligher Colorectal Surgery Unit, St. James's University Hospital, Leeds, UK.ORCID 0000-0001-5628-4880
Francesca DouglasThe John Goligher Colorectal Surgery Unit, St. James's University Hospital, Leeds, UK.
David JayneThe John Goligher Colorectal Surgery Unit, St. James's University Hospital, Leeds, UK.ORCID 0000-0002-8725-3283
David MeadsLeeds Institute for Health Sciences, University of Leeds, Leeds, UK.ORCID 0000-0003-1369-2483

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe global burden of colorectal cancer (CRC) is set to increase by 60% by 2030. An aging population and increasing treatment complexity add difficulties for patients and clinicians in CRC management. Patient preferences can be investigated using attribute-based stated preference (AbSP) techniques to explore trade-offs between different treatments. These techniques include discrete-choice experiments (DCEs), conjoint analysis and time-trade off (TTO) methods. This systematic review with a narrative synthesis aimed to determine the use and design of AbSP studies in CRC treatment and to identify patient choice themes.

methodsThe searches were performed using MEDLINE, Embase, PsycInfo and Cochrane Library in March 2021. All manuscripts featuring the use of AbSP techniques in CRC treatment were included. Data synthesis was performed using a narrative approach.

resultsThe search strategy returned 271 articles. Eighteen AbSP studies were included featuring 1890 patients and 296 clinicians. AbSP techniques compromised DCE (38.9%, n = 7), TTO (38.9%, n = 7) and conjoint analysis (22.2%, n = 4). Eleven studies (61.1%) involved piloting of tasks and the average task completion rate was 75%. CRC treatments included chemotherapy (33%, n = 6), combined treatments (33%, n = 6), surgery (17%, n = 3), targeted therapy (11%, n = 2) and radiotherapy (6%, n = 1). The most examined domain was physical health, investigated with 49 (59.8%) attributes.

conclusionsLife expectancy was the main attribute in chemotherapy treatment. With surgery, patients were willing to trade life-expectancy to avoid adverse outcomes or a permanent stoma. Communication skills, treatment cost, and clinicians' views were important attributes for patients in cancer services. Further research in the elderly population, and other quality of life domains, are needed to deliver patient-centred CRC care.

Indexed as

Colorectal NeoplasmsPatient PreferenceAgedChoice BehaviorDecision MakingHumansQuality of Lifecolonic neoplasmscolorectal neoplasmshumanspatient preferenceresearch

Identifiers

PMID35776854
PMCPMC9796068

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.