Evidence map›Paper›PMID 35776746›Full record

ArticlePloS one2022

Assumptions about patients seeking PrEP: Exploring the effects of patient and sexual partner race and gender identity and the moderating role of implicit racism.

Samuel R Bunting, Brian A Feinstein, Sarah K Calabrese, Aniruddha Hazra, Neeral K Sheth, Alex F Chen, Sarah S Garber

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Observational
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Samuel R BuntingDepartment of Psychiatry and Behavioral Neuroscience, The University of Chicago Medicine, Chicago, Illinois, United States of America.ORCID 0000-0003-2186-5460
Brian A FeinsteinDepartment of Psychology, College of Health Professions, Rosalind Franklin University, North Chicago, Illinois, United States of America.
Sarah K CalabreseDepartment of Psychological and Brain Sciences, The George Washington University, Washington, District of Columbia, United States of America.
Aniruddha HazraSection of Infectious Diseases and Global Health, Department of Medicine, The University of Chicago Medicine, Chicago, Illinois, United States of America.
Neeral K ShethDepartment of Psychiatry and Behavioral Sciences, Rush University Medical Center, Chicago, Illinois, United States of America.ORCID 0000-0003-2791-9028
Alex F ChenChicago Medical School, Rosalind Franklin University, North Chicago, Illinois, United States of America.
Sarah S GarberDepartment of Pharmaceutical Sciences, College of Pharmacy, Rosalind Franklin University, North Chicago, Illinois, United States of America.
Rosalind Franklin University of Medicine and Science · USUniversity of Chicago · USGeorge Washington University · USRush University Medical Center · US

Funding

Understanding and reducing HIV risk behavior and substance use among self-identified bisexual adolescent menK08DA045575 · NIDA · ROSALIND FRANKLIN UNIV OF MEDICINE & SCI · PI FEINSTEIN, BRIAN · 2018 to 2022
$837k
NIDA NIH HHS K08 DA045575
6 · The paper itself

Abstract

introductionDaily pre-exposure prophylaxis (PrEP) for HIV-prevention is an essential component of national plans to end the HIV epidemic. Despite its well-documented safety and effectiveness, PrEP prescription has not met the public health need. Significant disparities between White and Black people exist with respect to PrEP prescription, as do disparities between men and women. One factor contributing to these disparities is clinicians' assumptions about patients seeking PrEP.

methodsThe present study sought to investigate medical students' assumptions about patients seeking PrEP (anticipated increased condomless sex, extra-relational sex, and adherence to PrEP), and assumed HIV risk when presenting with their sexual partner. We systematically varied the race (Black or White) and gender (man or woman) of a fictional patient and their sexual partner. All were in serodifferent relationships including men who have sex with men (MSM), women (MSW), and women who have sex with men (WSM). Participants also completed an implicit association test measuring implicit racism against Black people. We evaluated the moderation effects of patient and partner race on assumptions as well as the moderated moderation effects of implicit racism.

resultsA total of 1,472 students participated. For MSM patients, having a Black partner was associated with higher assumed patient non-adherence to PrEP compared to a White partner, however a White partner was associated with higher assumed HIV risk. For MSW patients, a White male patient was viewed as being more likely to engage in more extra-relational sex compared to a Black male patient. For WSM patients, White women were assumed to be more likely to have condomless and extra-relational sex, be nonadherent to PrEP, and were at higher HIV risk. Overall, implicit racism was not related to negative assumptions about Black patients as compared to White patients based on patient/partner race. DISCUSSION: Medical education about PrEP for HIV prevention must ensure future health professionals understand the full range of patients who are at risk for HIV, as well as how implicit racial biases may affect assumptions about patients in serodifferent couples seeking PrEP for HIV prevention. As gatekeepers for PrEP prescription, clinicians' assumptions about patients seeking PrEP represent a barrier to access. Consistent with prior research, we identified minimal effects of race and implicit racism in an experimental setting.

Indexed as

Bias, ImplicitHIV InfectionsPre-Exposure ProphylaxisRacismSexual PartnersFemaleGender IdentityHomosexuality, MaleHumansMaleSexual and Gender Minorities

Identifiers

PMID35776746
PMCPMC9249206
OpenAlexW4283772845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.