SynthesisPloS one2022
Sepsis assessment and management in critically Ill adults: A systematic review.
Synthesis in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06475144 (Effects of an Online Escape Room on Enhancing Nurses' Knowledge, Clinical Reasoning, and Self-Efficacy Regarding Early Warning Signs of Sepsis), which is not on this map. Cited by 26 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Effects of an Online Escape Room on Enhancing Nurses' Knowledge, Clinical Reasoning, and Self-Efficacy Regarding Early Warning Signs of Sepsis: A Randomized Controlled Trial
Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- Diagnostic value of [European journal of nuclear medicine and molecular imaging · 2026Pooled it
- Early detection of sepsis using machine learning algorithms: a systematic review and network meta-analysis.Frontiers in medicine · 2024Pooled it
- mRNA nanotherapeutics for sepsis: immune modulation strategies and translational challenges.Journal of nanobiotechnology · 2026Review
- The relationship between urinary tract infections and sepsis: results from Mendelian randomization and MIMIC data study.World journal of urology · 2026Article
- Prioritized barriers to implementation of personalized immunotherapy for sepsis patients.Implementation science communications · 2026Article
- Reduced SNHG16 promotes sepsis-induced intestinal injury via the miR-15a-5p/AKT3 axis.BMC gastroenterology · 2026Article
- Influencing Factors of New-Onset Atrial Fibrillation in Sepsis Patients and Construction of a Nomogram Prediction Model: Based on LASSO Regression.International journal of general medicine · 2026Article
- Heterogeneity in Responding to Clinical Vignettes Depicting Sepsis Suggests That Non-Medical Data May Drive the Decision-Making Process.Healthcare (Basel, Switzerland) · 2025Article
- Evaluation of nurses' knowledge and practice regarding sepsis management: "A case study of adult ICU/HDU setting at CHUK".BMC nursing · 2025Article
- A LASSO-based integrative model of serum biomarkers and gene polymorphisms for predicting poor sepsis prognosis.Biomarkers in medicine · 2025Article
- The impact of duration below target mean arterial pressure value on mortality in critically ill patients.Pakistan journal of medical sciences · 2025Article
- Nurses' knowledge, attitudes, and decision-making related to sepsis assessment and management in Palestinian intensive care units.BMC nursing · 2025Article
- The diagnostic role of 2-[La Radiologia medica · 2025Article
- Evaluating Sepsis Management and Patient Outcomes: A Comprehensive Retrospective Study of Clinical and Treatment Data.Journal of clinical medicine · 2025Article
- Critical care nurses' knowledge, confidence, and clinical reasoning in sepsis management: a systematic review.BMC nursing · 2025Article
- Health-Related Quality of Life Among Patients Who Have Survived an Episode of Sepsis in the United States: A Systematic Review.Infectious diseases and therapy · 2025Review
- Endocrine and metabolic alterations in response to systemic inflammation and sepsis: a review article.Molecular medicine (Cambridge, Mass.) · 2025Review
- Psychometric Properties of the Barriers to and Facilitators of Implementing the Sepsis Six Care Bundle (BLISS-1) Questionnaire.Risk management and healthcare policy · 2025Article
- Be-SNAP: the Belgian Sepsis National Action Plan.Frontiers in public health · 2025Article
- Understanding ICU Nursing Knowledge, Perceived Barriers, and Facilitators of Sepsis Recognition and Management: A Cross-Sectional Study.Critical care explorations · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEarly assessment and management of patients with sepsis can significantly reduce its high mortality rates and improve patient outcomes and quality of life.
objectivesThe purposes of this review are to: (1) explore nurses' knowledge, attitude, practice, and perceived barriers and facilitators related to early recognition and management of sepsis, (2) explore different interventions directed at nurses to improve sepsis management.
methodsA systematic review method according to the PRISMA guidelines was used. An electronic search was conducted in March 2021 on several databases using combinations of keywords. Two researchers independently selected and screened the articles according to the eligibility criteria.
resultsNurses reported an adequate of knowledge in certain areas of sepsis assessment and management in critically ill adult patients. Also, nurses' attitudes toward sepsis assessment and management were positive in general, but they reported some misconceptions regarding antibiotic use for patients with sepsis, and that sepsis was inevitable for critically ill adult patients. Furthermore, nurses reported they either were not well-prepared or confident enough to effectively recognize and promptly manage sepsis. Also, there are different kinds of nurses' perceived barriers and facilitators related to sepsis assessment and management: nurse, patient, physician, and system-related. There are different interventions directed at nurses to help in improving nurses' knowledge, attitudes, and practice of sepsis assessment and management. These interventions include education sessions, simulation, decision support or screening tools for sepsis, and evidence-based treatment protocols/guidelines. DISCUSSION: Our findings could help hospital managers in developing continuous education and staff development training programs on assessing and managing sepsis in critical care patients.
conclusionNurses have poor to good knowledge, practices, and attitudes toward sepsis as well as report many barriers related to sepsis management in adult critically ill patients. Despite all education interventions, no study has collectively targeted critical care nurses' knowledge, attitudes, and practice of sepsis management.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.