Evidence map›Paper›PMID 35776545›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Real-time visualization of mRNA synthesis during memory formation in live mice.

Byung Hun Lee, Jae Youn Shim, Hyungseok C Moon, Dong Wook Kim, Jiwon Kim, Jang Soo Yook, Jinhyun Kim, Hye Yoon Park

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Neural substrate of conditioned stimulus for associative learning in the hippocampus.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Behavioral Training Procedures for Head-fixed Virtual Reality in Mice.Journal of visualized experiments : JoVE · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Synaptic Engram.Advances in neurobiology · 2024
    Review
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Byung Hun LeeDepartment of Physics and Astronomy, Seoul National University, Seoul 08826, Korea.ORCID 0000-0002-0001-4846
Jae Youn ShimDepartment of Physics and Astronomy, Seoul National University, Seoul 08826, Korea.ORCID 0000-0001-7332-4696
Hyungseok C MoonDepartment of Physics and Astronomy, Seoul National University, Seoul 08826, Korea.
Dong Wook KimDepartment of Physics and Astronomy, Seoul National University, Seoul 08826, Korea.
Jiwon KimCenter for Functional Connectomics, Brain Science Institute, Korea Institute of Science and Technology, Seoul 02792, Korea.ORCID 0000-0002-9864-6330
Jang Soo YookCenter for Functional Connectomics, Brain Science Institute, Korea Institute of Science and Technology, Seoul 02792, Korea.
Jinhyun KimCenter for Functional Connectomics, Brain Science Institute, Korea Institute of Science and Technology, Seoul 02792, Korea.ORCID 0000-0001-5429-505X
Hye Yoon ParkDepartment of Physics and Astronomy, Seoul National University, Seoul 08826, Korea.ORCID 0000-0003-4704-8178

Funding

Howard Hughes Medical InstituteWellcome TrustWellcome Trust (WT) 208468/Z/17/Z
6 · The paper itself

Abstract

Memories are thought to be encoded in populations of neurons called memory trace or engram cells. However, little is known about the dynamics of these cells because of the difficulty in real-time monitoring of them over long periods of time in vivo. To overcome this limitation, we present a genetically encoded RNA indicator (GERI) mouse for intravital chronic imaging of endogenous

Indexed as

CA1 Region, HippocampalCytoskeletal ProteinsMemoryNerve Tissue ProteinsRNA, MessengerAnimalsCalciumConditioning, ClassicalFearMiceMice, Inbred C57BLactivity regulated cytoskeletal-associated proteinCalciumCytoskeletal ProteinsNerve Tissue ProteinsRNA, MessengerArc mRNAengramin vivo imagingmemory tracevirtual reality

Identifiers

PMID35776545
PMCPMC9271212

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.