Evidence map›Paper›PMID 35776408›Full record

ArticleDermatology and therapy2022

Update on the Management of Pediatric Psoriasis: An Italian Consensus.

Ketty Peris, Anna Belloni Fortina, Luca Bianchi, Gabriella Fabbrocini, Paolo Gisondi, Anna Balato, Federico Bardazzi, Nicoletta Bernardini, Domenico Bonamonte, Maria Rita Bongiorno and 20 more

Open access · goldAbstract read
In one paragraph

Article in Dermatology and therapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 30 citations in OpenAlex.

  1. Long-term safety and efficacy of secukinumab in paediatric severe plaque psoriasis: 236-week, Phase 3 trial results.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026
    Trial
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

30 authors at 20 institutions in 1 country.

Ketty PerisUOC di Dermatologia, Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli-IRCCS, Rome, Italy.
Anna Belloni FortinaUnità di Dermatologia Pediatrica, Dipartimento di Medicina, Università di Padova, Padua, Italy.
Luca BianchiUOSD di Dermatologia, Fondazione Policlinico di Tor Vergata, Rome, Italy.
Gabriella FabbrociniDipartimento di Medicina Clinica e Chirurgia, Unità Operativa Complessa di Dermatologia, Università di Napoli Federico II, Naples, Italy.
Paolo GisondiDipartimento di Medicina, Sezione di Dermatologia e Venereologia dell'Università di Verona, Verona, Italy.
Anna BalatoDipartimento di Salute Mentale e Fisica e Medicina Preventiva, Università della Campania "Luigi Vanvitelli", Naples, Italy.
Federico BardazziDivisione di Dermatologia-IRCCS, Azienda Ospedaliera Universitaria Bologna, Bologna, Italy.
Nicoletta BernardiniDipartimento di Scienze e Biotecnologie Medico-Chirurgiche, Unità di Dermatologia "Daniele Innocenzi", Sapienza Università di Roma, Polo Pontino, Rome, Italy.
Domenico BonamonteDipartimento di Scienze Biomediche ed Oncologia Umana, Unità di Dermatologia, Università di Bari, Bari, Italy.
Maria Rita BongiornoSezione di Dermatologia, Dipartimento Promozione della Salute, Materno-Infantile, di Medicina Interna e Specialistica di Eccellenza "G. D'Alessandro" (PROMISE), Università di Palermo, Palermo, Italy.
Cinzia BuliganDipartimento di Medicina, Istituto di Dermatologia, Università di Udine, Udine, Italy.
Francesco CusanoUnità di Dermatologia, Ospedale Gaetano Rummo, Benevento, Italy.
Maria Beatrice De Felici Del GiudiceUnità di Dermatologia,, Azienda Ospedaliero-Universitaria di Parma, Università di Parma, Parma, Italy.
May El HachemUnità di Dermatololgia e Genodermatosi, Genetica e Malattie Rare, Ospedale Pediatrico del Bambino Gesù e Istituto di Ricerca, IRCCS, Rome, Italy.
Maria Concetta FargnoliDermatologia, Dipartimento di Scienze Cliniche Applicate e Biotecnologiche, Università dell'Aquila, L'Aquila, Italy.
Giulio GualdiDipartimento di Medicina e Scienze dell'Invecchiamento, Clinica Dermatologica, Università G. D'Annunzio, Chieti, Italy.
Claudio GuarneriDipartimento di Scienze Biomediche, Odontoiatriche e delle Immagini Morfologiche e Funzionali (BIOMORF), Clinica Dermatologica, Università degli Studi di Messina, Messina, Italy.
Katharina HanselSezione di Dermatologia, Dipartimento di Medicina e Chirurgia, Università di Perugia, Perugia, Italy.
Giovanna MalaraUnità di Dermatologia, Grande Ospedale Metropolitano "Bianchi Melacrino Morelli", Reggio Calabria, Italy.
Carlo MazzatentaUOSD Dermatologia Lucca, Azienda USL Toscana Nord Ovest, Lucca, Italy.
Giuseppe MicaliClinica Dermatologica, Università of Catania, Catania, Italy.
Alessandra NarcisiUOC Dermatologia, IRCCS Humanitas Rozzano-Milano, Milan, Italy.
Iria NeriUnità di Dermatologia, Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy.
Teresa OrangesDipartimento di Pediatria, Unità di Dermatologia, Ospedale Pediatrico Meyer, Florence, Italy.
Michele PanzoneAOU Città della Salute e Della Scienza di Torino, SC Dermatologia U, Divisione Pediatrica, Turin, Italy.
Aurora ParodiDiSSal, Sezione di Dermatologia, Universitaria di Genova, Ospedale-Policlinico San Martino IRCCS, Genoa, Italy.
Lucia RestanoUOC Dermatologia Pediatrica, Dipartimento Donna-Bambino-Neonato Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
Oriana SimonettiClinica Dermatologica, Dipartimento DISCLIMO, Università Politecnica delle Marche, Ancona, Italy.
Marina VenturiniDipartimento di Dermatologia, Università di Brescia e ASST-Spedali Civili di Brescia, Brescia, Italy.
Vito Di LerniaUnità di Dermatologia, Arcispedale Santa Maria Nuova, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy. vito.dilernia@ausl.re.it.ORCID http://orcid.org/0000-0002-8961-7108
Azienda USL di Bologna · ITAzienda ospedaliera "Bianchi-Melacrino-Morelli" · ITAzienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITAzienda Ospedaliera G.Rummo · ITAzienda Sanitaria Unità Locale di Reggio Emilia · ITAzienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia · ITAzienda Usl Toscana Centro · ITBambino Gesù Children's Hospital · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITMarche Polytechnic University · ITMeyer Children's Hospital · ITOspedale di Parma · ITOspedale Policlinico San Martino · ITPoliclinico Tor Vergata · ITSapienza University of Rome · ITUniversità Cattolica del Sacro Cuore · ITUniversity of Bari Aldo Moro · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Catania · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPsoriasis affects children with a considerable burden in early life. Treating pediatric psoriasis is challenging also because of the lack of updated specific guidelines. With the recent approval of several biologics for pediatric psoriasis and the ongoing COVID-19 pandemic, the management of young psoriatic patients is facing major changes. A revision of treatment recommendations is therefore needed.

methodsIn September 2021, a board of six Italian dermatologists convened to update treatment recommendations. The board issued evidence- and consensus-based statements covering relevant areas of pediatric psoriasis, namely: assessment of psoriasis severity, management of children with psoriasis, and treatment of pediatric psoriasis. To reach consensus, the statements were submitted to a panel of 24 experts in a Delphi process performed entirely via videoconference. A treatment algorithm was produced.

resultsThere was full consensus that psoriasis severity is determined by the extension/severity of skin lesions, site of lesions, and impact on patient quality of life. Agreement was reached on the need for a multidisciplinary approach to pediatric psoriasis and the importance of patient/parents education. The relevance of vaccinations, including COVID-19 vaccination, for psoriatic children was acknowledged by all participants. Management issues that initially failed to reach consensus included the screening for psoriasis comorbidities and early treatment with biologics to prevent them and the use of telemedicine to facilitate patient follow-up. There was full consensus that topical corticosteroids are the first choice for the treatment of mild pediatric psoriasis, while phototherapy and systemic therapy are used in children with moderate-severe psoriasis. According to the proposed treatment algorithm, biologics are the first line of systemic therapy.

conclusionsTargeted systemic therapies are changing the treatment of moderate-severe pediatric psoriasis, while topical corticosteroids continue to be the first choice for mild disease. Children-centered research is needed to further improve the treatment of pediatric psoriasis.

Indexed as

AdolescentsBiologicsChildrenCorticosteroid-sparingHealth-related quality of lifePediatric psoriasisPlaque psoriasisSystemic therapyTopical corticosteroids

Identifiers

PMID35776408
PMCPMC9247936
OpenAlexW4283763253

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.