Evidence map›Paper›PMID 35776254›Full record

ArticleAIDS and behavior2022

Prevalence and Risk Factors of PrEP Use Stigma Among Adolescent Girls and Young Women in Johannesburg, South Africa and Mwanza, Tanzania Participating in the EMPOWER Trial.

R J Munthali, A L Stangl, D Baron, I Barré, S Harvey, L Ramskin, M Colombini, N Naicker, S Kapiga, S Delany-Moretlwe and 1 more

Open access · hybridAbstract read
In one paragraph

Article in AIDS and behavior, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 4 countries.

R J MunthaliWits RHI, University of the Witwatersrand, Johannesburg, South Africa.
A L StanglInternational Center for Research on Women, Washington, DC, USA. alstangl@gmail.com.ORCID http://orcid.org/0000-0001-9325-5077
D BaronWits RHI, University of the Witwatersrand, Johannesburg, South Africa.
I BarréInternational Center for Research on Women, Washington, DC, USA.
S HarveyLondon School of Hygiene and Tropical Medicine, London, UK.
L RamskinWits RHI, University of the Witwatersrand, Johannesburg, South Africa.
M ColombiniUniversity of North Carolina, Chapel Hill, NC, USA.
N NaickerWits RHI, University of the Witwatersrand, Johannesburg, South Africa.
S KapigaUniversity of North Carolina, Chapel Hill, NC, USA.
S Delany-MoretlweWits RHI, University of the Witwatersrand, Johannesburg, South Africa.
EMPOWER study team
University of the Witwatersrand · ZAUniversity of North Carolina at Chapel Hill · USInternational Center for Research on Women · USLondon School of Hygiene & Tropical Medicine · GB

Funding

Department for International Development, UK Government PHGHZL69-14Evidence for HIV Prevention in Southern Africa (EHPSA) MM/EHPSA/WHC/05150015Medical Research Council MC_PC_MR/S008691/1South African Medical Research Council RFA-CC: TB/HIV/AIDS-01-2014
6 · The paper itself

Abstract

Adolescent girls and young women (AGYW) in sub-Saharan Africa may benefit from pre-exposure prophylaxis (PrEP), yet stigma may limit PrEP acceptance and continuation. We examined factors associated with PrEP use stigma among 307 participants of the EMPOWER trial (2016-2018), an unblinded randomized controlled trial among HIV-negative, AGYW, aged 16-24, in South Africa and Tanzania. The 6-item, brief-PrEP use stigma scale (B-PSS) had high internal reliability. At the end of the trial, 34.2% of study participants reported any PrEP use stigma. Three latent classes were observed, reflecting low (46.9%), medium (31.9%), and high (21.2%) reported PrEP use stigma. Disclosure of PrEP use to sexual partner and belief that PrEP prevents HIV were associated with less reported PrEP use stigma. Conversely, participants who reported fear and shame about people living with HIV were more likely to report PrEP use stigma. Our validated tool and findings will enable practitioners to identify AGYW at high risk of PrEP use stigma who may benefit from additional support.Pan African clinical trials registry PACTR202006754762723, 5 April 2020, retrospectively registered.

Indexed as

Anti-HIV AgentsHIV InfectionsPre-Exposure ProphylaxisAdolescentFemaleHumansPrevalenceReproducibility of ResultsRisk FactorsSouth AfricaTanzaniaAnti-HIV AgentsAdolescent girls and young women (AGYW)HIVPre-exposure prophylaxis (PrEP)StigmaSub-Saharan Africa

Identifiers

PMID35776254
PMCPMC9640431
OpenAlexW4283753000

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.