ArticleClinical oral investigations2022
Use of an applicator brush with high concentration bleaching gels.
Article in Clinical oral investigations, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- Influence of Different Protocols on In-Office Bleaching: Whiteness Difference and Hydrogen Peroxide Penetration.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025Trial
- Clinical evaluation of in-office bleaching with low, medium, and high concentrate hydrogen peroxide: a 6-month a double-blinded randomized controlled trial.Clinical oral investigations · 2025Trial
- In-office dental bleaching in adolescents using 6% hydrogen peroxide with different application tips: randomized clinical trial.Journal of applied oral science : revista FOB · 2023Trial
- Use of infrared photobiomodulation with low-level laser therapy for reduction of bleaching-induced tooth sensitivity after in-office bleaching: a double-blind, randomized controlled trial.Lasers in medical science · 2022Trial
- Effect of Applicator Brush Use on Color Change, Hydrogen Peroxide Penetration, and Gel Consumption in In-Office Bleaching: A Systematic Review and Meta-Analysis.Dentistry journal · 2026Review
- Do bleaching gels supplied in attachable syringes maintain their bleaching efficacy 72 hours after mixing?Clinical oral investigations · 2026Article
- Effect of violet and blue light activation on in-office bleaching with 6% hydrogen peroxide: color change, penetration into the pulp chamber and bleaching gel stability.Lasers in medical science · 2026Article
- Resin infiltration and in-office dental bleaching on different substrates: hydrogen peroxide penetration, color change, and enamel morphology- an in vitro study.Clinical oral investigations · 2025Article
- Impact of bleaching on white spot lesions: hydrogen peroxide permeability and color alteration.Clinical oral investigations · 2025Article
- Article
- Low and high hydrogen peroxide concentrations of in-office dental bleaching associated with violet light: an in vitro study.Clinical oral investigations · 2024Article
- The Effect of Different Bleaching Techniques Using 6% Hydrogen Peroxide: Penetration Inside the Pulp Cavity, Bleaching Efficacy and Toxicity.Brazilian dental journal · 2024Article
- Hydrogen Peroxide in the Pulp Chamber and Color Change in Maxillary Anterior Teeth After In-Office Bleaching.Brazilian dental journal · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
objectivesTo evaluate in vitro two high concentration self-mix bleaching gels (35% or 37.5%) with different application tips (with or without an applicator brush) during in-office bleaching. MATERIALS AND
methodsHealthy premolars were randomly assigned to five groups (n = 8): no treatment; 35% HP without applicator brush, 35% HP with applicator brush, 37.5% HP without applicator brush, and 37.5% HP with applicator brush. After the procedures, the concentration of HP transferred into the pulp chamber was evaluated using UV-Vis. The amount of gel used in each group was measured on a precision analytical balance. Color change (ΔE
resultsUsing a tip with an applicator brush expended less gel and left a lower amount of HP inside the pulp chamber compared to the tip without a brush for both bleaching gels (p < 0.0003), although no significant difference in color change was observed (p < 0.05). The 37.5% HP showed a more stable and less acidic pH and a lower amount of HP in the pulp chamber than the 35% HP (p < 0.00001).
conclusionThe HP penetration into the pulp chamber was lower when using an applicator with a brush tip than when using one with a conventional tip. As for the color, both tips were considered to lighten teeth. CLINICAL SIGNIFICANCE: For the application of a self-mixing high concentration in-office bleaching gel, a brush tip should be recommended because its use diminishes the penetration of HP into the pulp chamber and wastes less bleaching gel.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.