Evidence map›Paper›PMID 35776001›Full record

Trial reportTranslational behavioral medicine2022

Effectiveness of an integrated primary care intervention in improving psychosocial outcomes among Latino adults with diabetes: the LUNA-D study.

Sheila F Castañeda, Linda C Gallo, Melawhy L Garcia, Paulina M Mendoza, Angela P Gutierrez, Maria Lopez-Gurolla, Scott Roesch, Margaret S Pichardo, Fatima Muñoz, Gregory A Talavera

Erratum issued Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Translational behavioral medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT03983499 (Latinos Understanding the Need for Adherence in Diabetes), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03983499 nacompletednot on this map

Latinos Understanding the Need for Adherence in Diabetes

TypeinterventionalSponsorSan Diego State UniversityRan2015 to 2018Enrolled456ConditionsType 2 Diabetes, Glycemic Control, Cardiovascular Risk Factors, Psychological DistressArmsSpecial Intervention
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Precision Medicine in Type 2 Diabetes Mellitus: Utility and Limitations.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Sheila F CastañedaSouth Bay Latino Research Center, Chula Vista, CA, USA.ORCID 0000-0002-1975-0544
Linda C GalloSouth Bay Latino Research Center, Chula Vista, CA, USA.
Melawhy L GarciaCenter for Latino Community Health, Evaluation, and Leadership Training, Department of Health Science, California State University Long Beach, Long Beach, CA, USA.
Paulina M MendozaSouth Bay Latino Research Center, Chula Vista, CA, USA.
Angela P GutierrezSouth Bay Latino Research Center, Chula Vista, CA, USA.
Maria Lopez-GurollaSouth Bay Latino Research Center, Chula Vista, CA, USA.
Scott RoeschSouth Bay Latino Research Center, Chula Vista, CA, USA.
Margaret S PichardoCollege of Medicine, Howard University, Washington, D. C., USA.
Fatima MuñozDepartment of Research, San Ysidro Health, San Diego, CA, USA.
Gregory A TalaveraSouth Bay Latino Research Center, Chula Vista, CA, USA.
San Diego State University · USCalifornia State University, Long Beach · USHoward University · USSan Ysidro Health · US

Funding

Scripps Translational Science InstituteUL1TR002550 · NCATS · SCRIPPS RESEARCH INSTITUTE, THE · PI TOPOL, ERIC JEFFREY · 2018 to 2022
$28.9M
New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
Latinos Understanding the Need for Adherence in DiabetesR01NR014866 · NINR · SAN DIEGO STATE UNIVERSITY · PI TALAVERA, GREGORY A · 2014 to 2018
$2.9M
NCATS NIH HHS 5 U54 TR002550NCATS NIH HHS UL1 TR002550NIDDK NIH HHS 5 P30 DK111022NIDDK NIH HHS P30 DK111022NIH HHS R01NR014866NINR NIH HHS R01 NR014866
6 · The paper itself

Abstract

objectiveTo compare the effectiveness of usual care (UC) versus a culturally tailored integrated care model in improving mental health symptoms for Latino patients with Type 2 diabetes mellitus (T2DM).

methodsWe conducted a two-arm randomized controlled trial from 2015 to 2019 at a federally qualified health center. Participants were 456 adults ages 23-80 years who had a previous diagnosis of T2DM and were not currently using insulin. Participants were randomly assigned to Integrated Care Intervention (ICI; including behavioral/mental healthcare, medical visits, health education and care coordination) or UC; standard of care including referrals for health education and behavioral/mental health care where appropriate. Intention-to-treat, multilevel models were used to compare group × time changes in depression and anxiety symptoms (PHQ-8; GAD-7) and perceived stress (PSS-10) across 6 months.

resultsParticipant mean age was 55.7 years, 36.3% were male, and 63.7% were primarily Spanish speaking. Baseline sociodemographic factors and mental health symptoms across study arms were balanced. Significant group × time interaction effects were observed for anxiety and depression symptoms (p < .05). Within the ICI and UC groups, mean depression symptom changes were -0.93 and -0.39 (p < .01); anxiety symptom changes were -0.97 (p < .01) and -0.11 (p = .35); and perceived stress changes were -1.56 and -1.27 (p < .01), respectively.

conclusionsAlthough both ICI and UC showed decreases over time, the ICI group evidenced larger, statistically significant changes in both depression and anxiety. Adapted integrated models of behavioral and chronic disease management appear to be effective and could be considered for usual care practices. CLINICALTRIALS.GOV IDENTIFIER: NCT03983499.

Indexed as

Diabetes Mellitus, Type 2AdultAgedAged, 80 and overAnxiety DisordersFemaleHispanic or LatinoHumansMaleMental HealthMiddle AgedPrimary Health CareYoung AdultHispanic/LatinoIntegrated careMental health symptomsPrimary care

Identifiers

PMID35776001
PMCPMC9385125
OpenAlexW4283742694

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.