Evidence map›Paper›PMID 35775793›Full record

ArticleTurkish journal of anaesthesiology and reanimation2022

Cardiovascular Disease, Intensive Care, and Mortality in Coronavirus Disease 2019 Patients: A Meta-Analysis.

Zouina Sarfraz, Azza Sarfraz, Muzna Sarfraz, Iqra Zia, Moosa Zulfiqar Ali, Radhika Garimella, Sameer Saleem Tebha, Hafiza Hussain, Zainab Nadeem, Gaurav Patel

Open access · goldAbstract read
In one paragraph

Article in Turkish journal of anaesthesiology and reanimation, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Zouina SarfrazDepartment of Research - Publication, Fatima Jinnah Medical University, Lahore Pakistan.
Azza SarfrazDepartment of Paediatrics - Child Health, Aga Khan University, Karachi, Pakistan.
Muzna SarfrazCMH Medical College, Lahore, Pakistan.
Iqra ZiaCMH Medical College, Lahore, Pakistan.
Moosa Zulfiqar AliCMH Medical College, Lahore, Pakistan.
Radhika GarimellaDr. NTR University of Health Sciences, India.
Sameer Saleem TebhaDepartment of Anaesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Hafiza HussainDepartment of Research - Publication, Fatima Jinnah Medical University, Lahore Pakistan.
Zainab NadeemAga Khan University Faculty of Medicine, Karachi, Pakistan.
Gaurav PatelSmt NHL Municipal Medical College, Gujarat, India.
CMH Lahore Medical College and Institute of Dentistry · PKAga Khan University · PKFatima Jinnah Medical University · PKDr. NTR University of Health Sciences · INJinnah Medical & Dental College · PKSmt. N.H.L. Municipal Medical College · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCoronavirus disease 2019 is caused by severe acute respiratory syndrome coronavirus-2. The coronavirus disease 2019 pandemic has imparted an extraordinary burden on the intensive care services, which is likely to echo in pandemic and critical care management glob- ally. We aim to meta-analyze mortality outcomes in cardiovascular disease patients and groups receiving corticosteroids therapy, intensive care admission status during coronavirus disease 2019 hospitalization and groups receiving corticosteroid therapy, and lastly, mortality outcomes in mechanically ventilated patients. Finally, we collate a coronavirus disease 2019 field algorithm for ST-elevation myocardial infarction critical care.

methodsPubMed databases were searched for relevant observational studies with MeSH terms including, "cardiovascular disease," "COVID-19," "intensive care," "mortality," and "mechanical ventilation." A random-effect model was used to calculate the risk ratio, using RevMan V5.3.

resultsA total of 67 622 patients were included with 10 076 participants in the cardiovascular disease group. Overall, the mean age of the participants in the studies was 60 ± 1.6 years and 52.1% were female. A higher death risk was found in cardiovascular disease patients during and after coronavirus disease 2019 infection (risk ratio = 2.43, 95% CI = 1.74 to 3.41, P < .0001). Mechanical ventilation was likened to worsen mortality rates at any time during the hospital stay (risk ratio = 5.32, 95% CI = 3.89 to 7.29, P < .0001). Publication bias was not observed and high methodological qualities were included.

conclusionsCardiovascular disease imparts a high burden on intensive care leading to high mortality among coronavirus disease 2019 patients. It is essential that myocardial infarctions in the acute care setting, and conditions such as hypertension and coronary artery diseases, are closely monitored while leading coronavirus disease 2019 hospitalization protocols.

Identifiers

PMID35775793
PMCPMC9629195
OpenAlexW4282838881

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.