ArticleExperimental biology and medicine (Maywood, N.J.)2022
Contusion concomitant with ischemia injury aggravates skeletal muscle necrosis and hinders muscle functional recovery.
Article in Experimental biology and medicine (Maywood, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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Who cites it
8 citing papers in PubMed, 7 citations in OpenAlex.
- An investigation into the cellular-level adverse effects of tourniquet use on the infrapatellar fat pad in primary total knee arthroplasty: A prospective randomized study.Acta orthopaedica et traumatologica turcica · 2023Trial
- Muscle-Nerve Signaling and Neurogenic Inflammation in Temporomandibular Disorders: Potential Contributions of Occlusal Interference and Other Peripheral Triggers.Dentistry journal · 2026Review
- The predictive value of the lactate/albumin ratio combined with APACHE II and injury severity score for short-term prognosis in patients with polytrauma.European journal of medical research · 2025Article
- Epidemiology and prognostic factors of necrotizing fasciitis in resource-limited regions based on 119 cases.Scientific reports · 2025Article
- SAT1/ALOX15 Signaling Pathway Is Involved in Ferroptosis After Skeletal Muscle Contusion.International journal of molecular sciences · 2024Article
- Combined effect of intermittent hemostasis and a modified external hemorrhage control device in a lethal swine model.Heliyon · 2024Article
- Betulin Accelerated the Functional Recovery of Injured Muscle in a Mouse Model of Muscle Contusion.International journal of medical sciences · 2024Article
- Alignment, cross linking, and beyond: a collagen architect's guide to the skeletal muscle extracellular matrix.American journal of physiology. Cell physiology · 2023Review
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Contusion concomitant with ischemia injury to skeletal muscles is common in civilian and battlefield trauma. Despite their clinical importance, few experimental studies on these injuries are reported. The present study established a rat skeletal muscle contusion concomitant with ischemia injury model to identify skeletal muscle alterations compared with contusion injury or ischemia injury. Macroscopic and microscopic morphological evaluation showed that contusion concomitant with ischemia injury aggravated muscle edema and hematoxylin-eosin (HE) injury score at 24 h postinjury. Serum creatine kinase (CK) and lactate dehydrogenase (LDH) levels, together with gastrocnemius muscle (GM) tumor necrosis factor-alpha (TNF-α) content elevated at 24 h postinjury too. During the 28-day follow-up, electrophysiological and contractile impairment was more severe in the contusion concomitant with ischemia injury group. In addition, contusion concomitant with ischemia injury decreased the percentage of larger (600-3000 μm
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