Evidence map›Paper›PMID 35775506›Full record

ArticleNeuropsychopharmacology reports2022

Development and acceptability of a decision aid for major depressive disorder considering discontinuation of antidepressant treatment after remission.

Yumi Aoki, Yoshikazu Takaesu, Hajime Baba, Jun-Ichi Iga, Hikaru Hori, Takeshi Inoue, Kazuo Mishima, Aran Tajika, Masaki Kato

Open access · goldAbstract read
In one paragraph

Article in Neuropsychopharmacology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 9 institutions in 1 country.

Yumi AokiDepartment Psychiatric and Mental Health Nursing, Graduate School of Nursing, St. Luke's International University, Tokyo, Japan.ORCID 0000-0002-2674-0707
Yoshikazu TakaesuDepartment of Neuropsychiatry, Graduate School of Medicine, University of the Ryukyus, Okinawa, Japan.ORCID 0000-0002-9169-3249
Hajime BabaDepartment of Psychiatry, Juntendo Koshigaya Hospital, Juntendo University Faculty of Medicine, Saitama, Japan.
Jun-Ichi IgaDepartment of Neuropsychiatry, Molecules and Function, Ehime University Graduate School of Medicine, Ehime, Japan.ORCID 0000-0003-4409-3096
Hikaru HoriDepartment of Psychiatry, Faculty of Medicine, Fukuoka University, Fukuoka, Japan.
Takeshi InoueDepartment of Psychiatry, Tokyo Medical University, Tokyo, Japan.ORCID 0000-0001-5248-1289
Kazuo MishimaDepartment of Neuropsychiatry, Akita University Graduate School of Medicine, Akita, Japan.
Aran TajikaDepartment of Health Promotion and Human Behavior, School of Public Health, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Masaki KatoDepartment of Neuropsychiatry, Kansai Medical University, Osaka, Japan.ORCID 0000-0001-6727-7272
Akita University · JPEhime University · JPFukuoka University · JPJuntendo University · JPKansai Medical University · JPKyorin University · JPKyoto University · JPSt. Luke's International University · JPTokyo Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimWhile evidence-based antidepressant treatment is available for major depressive disorder, standard approaches for discontinuation of antidepressants after remission have not yet been established. Decision aids are structured clinical tools that facilitate shared decision-making between patients and healthcare providers. This study aimed to describe the development process and acceptability of decision aids for major depressive disorder following discontinuation of antidepressant treatment after remission.

methodsWe systematically developed a decision aids according to the International Patient Decision Aid Standards. First, a decision aids prototype was created using the results of a systematic review and meta-analysis previously conducted to identify the consequences of continuing and discontinuing antidepressant treatment. Second, a mixed-methods questionnaire (alpha acceptability testing) was administered to patients and healthcare providers to improve the decision aids prototype and develop it into a final version acceptable for clinical settings.

resultsOur decision aids consisted of a description of major depressive disorder, the option to continue or discontinue antidepressant treatment, the advantages and disadvantages of each option, the consequences of each option, and value clarification exercises for each option. The patients (n = 22) reported that the decision aids had acceptable language (91%), adequate information (91%), and a well-balanced presentation (95%). Healthcare providers (n = 20) provided favorable feedback. The final decision aids fulfilled all six International Patient Decision Aid Standards qualifying criteria.

conclusionWe successfully developed a decision aids for discontinuation of antidepressant treatment after remission, which could be used during the shared decision-making process. Further studies are needed to verify the effects of using the decision aids during the shared decision-making process.

Indexed as

Major Depressive DisorderAntidepressive AgentsDecision Support TechniquesHumansSurveys and QuestionnairesAntidepressive Agentsantidepressantdecision aidsdepressionremissionshared decision-making

Identifiers

PMID35775506
PMCPMC9515698
OpenAlexW4283755212

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.