Evidence map›Paper›PMID 35775311›Full record

Trial reportClinical oral implants research2022

Non-surgical mechanical therapy of peri-implantitis with or without repeated adjunctive diode laser application. A 6-month double-blinded randomized clinical trial.

Andrea Roccuzzo, Sabrina Klossner, Alexandra Stähli, Jean-Claude Imber, Sigrun Eick, Anton Sculean, Giovanni E Salvi

Open access · hybridAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Clinical oral implants research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
9.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 56 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  9. Observational
  10. Article
  11. Review
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  15. Article
  16. Peri-Implantitis.Dentistry journal · 2024
    Review
  17. Article
  18. Surgical treatment of peri-implantitis.British dental journal · 2024
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Andrea RoccuzzoDepartment of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0002-8079-0860
Sabrina KlossnerDepartment of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.
Alexandra StähliDepartment of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0002-5631-3300
Jean-Claude ImberDepartment of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.
Sigrun EickDepartment of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.
Anton SculeanDepartment of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.
Giovanni E SalviDepartment of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.ORCID https://orcid.org/0000-0001-5523-3192
University of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe objective of this study is to investigate the outcomes following non-surgical therapy of peri-implantitis (PI) with or without adjunctive diode laser application. MATERIALS AND

methodsA double-blinded randomized controlled clinical trial was carried out in 25 subjects with 25 implants diagnosed with PI. Following curettage of granulation tissue, test implants (T) were treated with adjunctive application of a diode laser for 90 s (settings: 810 nm, 2.5 W, 50 Hz, 10 ms), while at control implants (C) non-activated adjunctive diode laser was applied. The entire treatment procedure was performed at days 0 (i.e., baseline), 7 and 14. The primary outcome measure was change in mean pocket probing depth (PPD). Clinical and microbiological outcomes, as well as host-derived inflammatory markers were evaluated at baseline, 3 and 6 months, while radiographic outcomes were assessed at baseline and at the 6-month follow-up.

resultsNo statistically significant differences with respect to baseline patient characteristic were observed. After 6 months, both test and control implants yielded statistically significant PPD changes compared with baseline (T: 1.28 and C: 1.47 mm) but without statistically significant difference between groups (p = .381). No statistically significant changes in peri-implant marginal bone levels were detected (p = .936). No statistically significant differences between test and control implants were observed with respect to microbiological and host-derived parameters (p > .05). At the 6-month follow-up, treatment success was observed in 41.7% (n = 5) of test and 46.2% (n = 6) of control patients, respectively (p = .821).

conclusionRepeated adjunctive application of diode laser in the non-surgical management of PI failed to provide significant benefits compared with mechanical instrumentation alone.

Indexed as

Dental ImplantsPeri-ImplantitisPhotochemotherapyDental CareHumansLasers, SemiconductorTreatment OutcomeDental Implantsclinical trialnon-surgical therapyperi-implantitis

Identifiers

PMID35775311
PMCPMC9546299
OpenAlexW4283739232

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.