Evidence map›Paper›PMID 35775125›Full record

ArticleInternational journal of STD & AIDS2022

STI prevalence, incidence, and partner notification among women in a periconception HIV prevention program in Uganda.

Pooja Chitneni, Winnie Muyindike, Mwebesa Bosco Bwana, Moran Owembabazi, Kasey O'Neil, Paul Kato Kalyebara, Bethany Hedt-Gauthier, David R Bangsberg, Jeanne M Marrazzo, Angela Kaida and 2 more

Open access · greenAbstract read
In one paragraph

Article in International journal of STD & AIDS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Pooja ChitneniDivision of Infectious Diseases, 2348Massachusetts General Hospital, Boston, MA, USA.ORCID 0000-0002-5648-3852
Winnie Muyindike108123Mbarara Regional Referral Hospital and Mbarara University of Science and Technology, Mbarara, Uganda.
Mwebesa Bosco Bwana108123Mbarara Regional Referral Hospital and Mbarara University of Science and Technology, Mbarara, Uganda.
Moran Owembabazi108123Mbarara Regional Referral Hospital and Mbarara University of Science and Technology, Mbarara, Uganda.
Kasey O'NeilDivision of Infectious Diseases, 2348Massachusetts General Hospital, Boston, MA, USA.
Paul Kato Kalyebara108123Mbarara Regional Referral Hospital and Mbarara University of Science and Technology, Mbarara, Uganda.
Bethany Hedt-GauthierDepartment of Global Health and Social Medicine, 1811Harvard Medical School, Boston, MA, USA.
David R Bangsberg143856OHSU PSU School of Public Health, Portland, OR, USA.
Jeanne M MarrazzoDivision of Infectious Diseases, 9968University of Alabama, Birmingham, AL, USA.
Angela Kaida1763Simon Fraser University, Burnaby, British Columbia, Canada.
Jessica E HabererHarvard Medical School, Boston, MA, USA.
Lynn T MatthewsDivision of Infectious Diseases, 9968University of Alabama, Birmingham, AL, USA.
Mbarara University of Science and Technology · UGHarvard University · USUniversity of Alabama at Birmingham · USBrigham and Women's Hospital · USSimon Fraser University · CA

Funding

Partnership for Global Health Research Training Program (Renewal)-Supplement for OBSSR, NCI, NCI-AIDS and NIDCDD43TW010543 · FIC · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Wafaie W Fawzi, DAVIDSON HOWES HAMER · 2017 to 2026
$12.1M
PROGRAM FOR AIDS CLINICAL RESEARCH TRAINING (PACRT)T32AI007433 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI MARK J SIEDNER · 1992 to 2026
$11.4M
Optimizing mHealth for adherence monitoring and interventionK24MH114732 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI HABERER, JESSICA ELIZABETH · 2017 to 2021
$800k
FIC NIH HHS D43 TW010543NIAID NIH HHS T32 AI007433NIMH NIH HHS K24 MH114732
6 · The paper itself

Abstract

backgroundWe provided sexually transmitted infection (STI) screening and facilitated partner notification and treatment among women participating in a periconception HIV prevention program in southwestern Uganda to understand follow-up STI incidence.

methodsWomen at-risk for HIV exposure while planning for pregnancy completed laboratory screening for chlamydia, gonorrhea, trichomoniasis, and syphilis at enrollment and 6 months of follow-up and/or incident pregnancy; facilitated partner notification and treatment were offered for those with positive tests. We performed a logistic regression to determine correlates of follow-up STI.

resultsNinety-four participants completed enrollment STI screening with a median age of 29 (IQR 26-34); 23 (24%) had ≥1 STI. Of the 23 participants with enrollment STI(s), all completed treatment and 19 (83%) returned for follow-up; 18 (78%) reported delivering partner notification cards and discussing STIs with partner(s), and 14 (61%) reported all partners received STI treatment. Of the 81 (86%) who successfully completed follow-up STI screening, 17 (21%) had ≥1 STI. The STI incidence rate was 29.0 per 100 person-years. In univariable regression analysis, enrollment STI, younger age, less education, and alcohol consumption were all significantly associated with follow-up STI.

conclusionsWe demonstrated high enrollment and follow-up STI rates and moderate participant-reported partner treatment among women planning for pregnancy in Uganda despite partner notification and treatment. Novel STI partner notification and treatment interventions are needed to decrease the STI burden, especially among women planning for and with pregnancy.

Indexed as

Chlamydia InfectionsGonorrheaHIV InfectionsSexually Transmitted DiseasesContact TracingFemaleHumansIncidencePregnancyPrevalenceUgandaAfricachlamydia (Chlamydia trachomatis)epidemiologygonorrhea (Neisseria gonorrhoeae)syphilis (Treponema pallidum)

Identifiers

PMID35775125
PMCPMC11871948
OpenAlexW4283752677

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.