Evidence map›Paper›PMID 35775079›Full record

ReviewFrontiers in molecular biosciences2022

New Insights on Ferroptosis and Gynecological Malignancies.

Ruiqi Fan, Yujun Sun, Mengxue Wang, Qian Wang, Aifang Jiang, Tingting Yang

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ruiqi FanCenter of Reproductive Medicine, Affiliated Hospital of Weifang Medical University, Weifang, China.
Yujun SunCenter of Reproductive Medicine, Affiliated Hospital of Weifang Medical University, Weifang, China.
Mengxue WangCenter of Reproductive Medicine, Affiliated Hospital of Weifang Medical University, Weifang, China.
Qian WangCenter of Reproductive Medicine, Affiliated Hospital of Weifang Medical University, Weifang, China.
Aifang JiangCenter of Reproductive Medicine, Affiliated Hospital of Weifang Medical University, Weifang, China.
Tingting YangCenter of Reproductive Medicine, Affiliated Hospital of Weifang Medical University, Weifang, China.
Weifang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ferroptosis is a new type of cell death different from apoptosis and necrosis, which can regulate the accumulation of lipid peroxidation through different pathways, ultimately leading to cell death. An increasing number of studies have revealed that the relationship between ferroptosis and cancer is extremely complex, which holds promise as a new treatment. In gynecological malignancies, ferroptosis has been found to have excellent antitumor activity, which can regulate the proliferation, metastasis and radiochemotherapy resistance. With the continuous progress of research, nanodrugs, gene therapy and other new therapeutic techniques for inducing ferroptosis have been proposed. However, the study of ferroptosis in gynecological malignancies is still in its infancy, and further research is needed to design safe and effective cancer therapies based on ferroptosis. This article reviews the mechanism of ferroptosis and the latest research progress and prospects in gynecological malignancies.

Indexed as

ferroptosisgynecological malignanciesiron metabolismnanotechnologyradiochemotherapy resistancereactive oxygen species

Identifiers

PMID35775079
PMCPMC9237217
OpenAlexW4282840379

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.