Evidence map›Paper›PMID 35774863›Full record

ReviewFrontiers in chemistry2022

Advanced Polymeric Nanoagents for Oral Cancer Theranostics: A Mini Review.

Guan-Meng Zhang, Shao-Chen Nie, Zhao-Yuan Xu, Ya-Ru Fan, Mai-Ning Jiao, He-Jing Miao, Su-Xia Liang, Ying-Bin Yan

Abstract readReview
In one paragraph

Review in Frontiers in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Innovative nanoparticle strategies for treating oral cancers.Medical oncology (Northwood, London, England) · 2025
    Review
  5. Review
  6. Article
  7. Review
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Guan-Meng ZhangDepartment of Oromaxillofacial-Head and Neck Surgery, Tianjin Stomatological Hospital, Hospital of Stomatology, Nankai University, Tianjin, China.
Shao-Chen NieTianjin Medical University, Tianjin, China.
Zhao-Yuan XuDepartment of Oromaxillofacial-Head and Neck Surgery, Tianjin Stomatological Hospital, Hospital of Stomatology, Nankai University, Tianjin, China.
Ya-Ru FanTianjin Medical University, Tianjin, China.
Mai-Ning JiaoTianjin Medical University, Tianjin, China.
He-Jing MiaoTianjin Medical University, Tianjin, China.
Su-Xia LiangTianjin Key Laboratory of Oral and Maxillofacial Function Reconstruction, Tianjin Stomatological Hospital, Hospital of Stomatology, Nankai University, Tianjin, China.
Ying-Bin YanDepartment of Oromaxillofacial-Head and Neck Surgery, Tianjin Stomatological Hospital, Hospital of Stomatology, Nankai University, Tianjin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral cancer is one of the most common tumours in the world threatening human life and health. The 5-years survival rate of patients with oral cancer has not been improved significantly for many years. The existing clinical diagnostic methods rarely achieve early diagnosis due to deficiencies such as lack of sensitivity. Most of the patients have progressed to the advanced stages when oral cancer is detected. Unfortunately, the traditional treatment methods are usually ineffective at this stage. Therefore, there is an urgent need for more effective and precise techniques for early diagnosis and effective treatment of oral cancer. In recent decades, nanomedicine has been a novel diagnostic and therapeutic platform for various diseases, especially cancer. The synthesis and application of various nanoagents have emerged at the right moment. Among them, polymer nanoagents have unique advantages, such as good stability, high biosafety and high drug loading, showing great potential in the early accurate diagnosis and treatment of tumours. In this review, we focus on the application of advanced polymeric nanoagents in both the diagnosis and treatment of oral cancer. Then, the future therapy strategies and trends for polymeric nanoagents applied to oral cancer are discussed, with the hope that more advanced nanomedical technology will be applied to oral cancer research and promote the development of stomatology.

Indexed as

cancer theranosticsnanomedicineoral cancerpolymer nanoagentstargeted delivery

Identifiers

PMID35774863
PMCPMC9237336

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.