Evidence map›Paper›PMID 35774835›Full record

ArticleActa informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH2022

Molecular Docking Approach of Bryophyllum Pinnatum Compounds as Atherosclerosis Therapy By Targeting Adenosine Monophosphate-Activated Protein Kinase and Inducible Nitric Oxide Synthase.

Yuyun Yuniwati, Mokhamad Fahmi Rizki Syaban, Salsabila Ghina Anoraga, Faradilah Lukmana Sabila

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yuyun YuniwatiDepartment of Radiology, Saiful Anwar General Hospital-Faculty of Medicine, Brawijaya Univesity, Malang, Indonesia.
Mokhamad Fahmi Rizki SyabanFaculty of Medicine, Brawijaya Univesity, Malang, Indonesia.
Salsabila Ghina AnoragaFaculty of Medicine, Brawijaya Univesity, Malang, Indonesia.
Faradilah Lukmana SabilaFaculty of Medicine, Brawijaya Univesity, Malang, Indonesia.
University of Brawijaya · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Objective: This research aims conducted to know the potential of Methods: We employed a molecular docking technique to interact active compounds of Results: Bryophillin B was an active compound that possesses significant binding to AMPK and iNOS. It had same binding pocket as native ligand, and Bryophyllin B has a stronger interaction with AMPK. Based on the RMSF, the interaction biding complex Bryophyllin B with AMPK and iNOS were stable. Conclusion: Bryophillin B was predicted to have potential therapy for atherosclerosis disease.

Indexed as

AMPKBryophyllum pinnatumHerbal medicineiNOSIn Silico

Identifiers

PMID35774835
PMCPMC9233472
OpenAlexW4283767686

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.