Evidence map›Paper›PMID 35774591›Full record

ArticleFunction (Oxford, England)2022

The Link Between Childhood Adversity and Cardiovascular Disease Risk: Role of Cerebral and Systemic Vasculature.

Paula Rodriguez-Miguelez, Jacob Looney, Marsha Blackburn, Jeffrey Thomas, Jennifer S Pollock, Ryan A Harris

Abstract read
In one paragraph

Article in Function (Oxford, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Skin-deep resilience in Black youth: Striving and sleep reactivity to daily stress.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Observational
  10. Central stress pathways in the development of cardiovascular disease.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2024
    Review
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Paula Rodriguez-MiguelezDepartment of Kinesiology and Health Sciences, Virginia Commonwealth University, Richmond 23284, VA, USA.ORCID 0000-0003-3582-4483
Jacob LooneyGeorgia Prevention Institute, Augusta University, Augusta 30912, Georgia, USA.
Marsha BlackburnGeorgia Prevention Institute, Augusta University, Augusta 30912, Georgia, USA.
Jeffrey ThomasGeorgia Prevention Institute, Augusta University, Augusta 30912, Georgia, USA.
Jennifer S PollockSchool of Medicine, University of Alabama at Birmingham, Birmingham 35294, Alabama, USA.ORCID 0000-0003-1956-0449
Ryan A HarrisGeorgia Prevention Institute, Augusta University, Augusta 30912, Georgia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adverse childhood experiences (ACEs) are traumatic events during the first years of life that are associated with a higher risk of developing cardiovascular disease (CVD) during adulthood. The medial prefrontal cortex (mPFC) is a core region in the brain that modulates emotions and is directly involved in the cardiovascular response to stress by increasing vascular resistance. In the present study we examined the relationship between ACEs, mPFC and peripheral vascular function. Forty-five, adults (33±5 yrs.) participated in the present study to evaluate cerebral hemodynamics and peripheral vascular function. The impact of adverse experiences was evaluated through the ACE questionnaire. Among those that experienced ACEs (ACE group, n = 22), there was a significantly (

Indexed as

Adverse Childhood ExperiencesCardiovascular DiseasesAdultHemodynamicsHumansSurveys and Questionnairesadverse childhood eventcardiovacularcerebral blood flownitric oxidevascular function

Identifiers

PMID35774591
PMCPMC9228651

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.