Evidence map›Paper›PMID 35774580›Full record

ArticleFrontiers in public health2022

Prevalence and Molecular Characterization of Metallo β-Lactamase Producing Gram-Negative Pathogens Causing Eye Infections.

Gunasekaran Rameshkumar, Ranjithkumar Dhandapani, Prajna Lalitha, Siva Ganesa Karthikeyan Rajapandian, Velmurugan Palanivel, Sathiamoorthi Thangavelu, Abdullah A Alyousef, Thamer Albalawi, Pravej Alam, Mohammad Zubair and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Antibiotics (Basel, Switzerland) · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 2 countries.

Gunasekaran RameshkumarMedical Microbiology Laboratory, Department of Microbiology, Alagappa University, Karaikudi, India.
Ranjithkumar DhandapaniMedical Microbiology Laboratory, Department of Microbiology, Alagappa University, Karaikudi, India.
Prajna LalithaDepartment of Ocular Microbiology, Aravind Eye Hospital, Madurai, India.
Siva Ganesa Karthikeyan RajapandianDepartment of Ocular Microbiology, Aravind Eye Hospital, Madurai, India.
Velmurugan PalanivelCentre for Material Engineering and Regenerative Medicine Bharath Institute of Higher Education, Chennai, India.
Sathiamoorthi ThangaveluMedical Microbiology Laboratory, Department of Microbiology, Alagappa University, Karaikudi, India.
Abdullah A AlyousefClinical Laboratory Sciences Department, College of Applied Medical Sciences, King Saud University, Riyadh, Saudi Arabia.
Thamer AlbalawiDepartment of Biology, College of Sciences and Humanities, Prince Sattam Bin Andulaziz University, Alkharj, Saudi Arabia.
Pravej AlamDepartment of Biology, College of Sciences and Humanities, Prince Sattam Bin Andulaziz University, Alkharj, Saudi Arabia.
Mohammad ZubairDepartment of Medical Microbiology, Faculty of Medicine, University of Tabuk, Tabuk, Saudi Arabia.
Fayez M SalehDepartment of Medical Microbiology, Faculty of Medicine, University of Tabuk, Tabuk, Saudi Arabia.
Fuad Abdullah AlatawiDepartment of Biology, Faculty of Science, University of Tabuk, Tabuk, Saudi Arabia.
Fohad M HusainDepartment of Food Science and Nutrition, King Saud University, Riyadh, Saudi Arabia.
Alagappa University · INUniversity of Tabuk · SAAravind Eye Hospital · INKing Saud University · SAPrince Sattam Bin Abdulaziz University · SABharath University · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Metallo β-lactamases (MβL) production is a worldwide problem, particularly in gram-negative bacteria. As scanty data is available on the prevalence of MBL, the present study is being undertaken to determine the prevalence, antibacterial sensitivity patterns, and molecular characterization of MβL associated resistant genes in gram-negative bacteria isolated from ocular infections. Material and Methods: At a tertiary eye care center in south India, 359 gram-negative pathogens, 200 isolates from eye infections, and 159 isolates from normal flora of the eye were studied. A gold standard microbiology method was used to identify the isolates. An antibiotic double disc synergy test and a combination disc test were used to detect MβL production. Multiplex PCR was used to investigate the molecular characteristics of the MβL encoding genes Results: Of the 359 gram-negative bacterial pathogens, Conclusion: The emerging MβLs mediated resistance among

Indexed as

EndophthalmitisEye InfectionsAnti-Bacterial Agentsbeta-LactamasesEscherichia coliGram-Negative BacteriaHumansMicrobial Sensitivity TestsPrevalencePseudomonas aeruginosaAnti-Bacterial Agentsbeta-LactamasesEnterobacteriaceaegram-negative bacilliMetallo β-lactamasesnon-Enterobacteriaceaenormal flora

Identifiers

PMID35774580
PMCPMC9237426
OpenAlexW4282835088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.