Evidence map›Paper›PMID 35774419›Full record

ArticleTransplantation direct2022

Long-term Survival Following Heart Transplantation for Chagas Versus Non-Chagas Cardiomyopathy: A Single-center Experience in Northeastern Brazil Over 2 Decades.

Jefferson L Vieira, Maria G V Sobral, Francisco Y Macedo, Raquel S Florêncio, Germana P L Almeida, Glauber G Vasconcelos, Juliana R Fernandes, Laura L E Marinho, Daniel F M Trompieri, Tilak K R Pasala and 2 more

Open access · goldAbstract read
In one paragraph

Article in Transplantation direct, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Jefferson L VieiraHeart Failure Division, Hospital de Messejana Dr Carlos Alberto Studart, Fortaleza, Ceará, Brazil.
Maria G V SobralHeart Failure Division, Hospital de Messejana Dr Carlos Alberto Studart, Fortaleza, Ceará, Brazil.
Francisco Y MacedoStructural and Congenital Heart Center, Hackensack University Medical Center, Hackensack, NJ.
Raquel S FlorêncioHeart Failure Division, Hospital de Messejana Dr Carlos Alberto Studart, Fortaleza, Ceará, Brazil.
Germana P L AlmeidaHeart Failure Division, Hospital de Messejana Dr Carlos Alberto Studart, Fortaleza, Ceará, Brazil.
Glauber G VasconcelosHeart Failure Division, Hospital de Messejana Dr Carlos Alberto Studart, Fortaleza, Ceará, Brazil.
Juliana R FernandesHeart Failure Division, Hospital de Messejana Dr Carlos Alberto Studart, Fortaleza, Ceará, Brazil.
Laura L E MarinhoHeart Failure Division, Hospital de Messejana Dr Carlos Alberto Studart, Fortaleza, Ceará, Brazil.
Daniel F M TrompieriHeart Failure Division, Hospital de Messejana Dr Carlos Alberto Studart, Fortaleza, Ceará, Brazil.
Tilak K R PasalaStructural and Congenital Heart Center, Hackensack University Medical Center, Hackensack, NJ.
Juan A C MejiaHeart Failure Division, Hospital de Messejana Dr Carlos Alberto Studart, Fortaleza, Ceará, Brazil.
João D Souza-NetoHeart Failure Division, Hospital de Messejana Dr Carlos Alberto Studart, Fortaleza, Ceará, Brazil.
Hospital de Messejana · BRHackensack University Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Data on post-heart transplant (HT) survival of patients with Chagas cardiomyopathy (CC) are scarce. We sought to evaluate post-HT survival in patients with CC as compared with other causes of heart failure across different eras of HT. Methods: We conducted a retrospective, cohort study of 376 adult HT recipients between October 1997 and November 2019. Participants were classified according to the etiology of heart failure as CC (N = 66), nonischemic cardiomyopathy (N = 214), and ischemic cardiomyopathy (N = 96), and according to the era of HT as early (1997-2009), recent (2010-2014), and current era (2015-2019). Results: After a mean follow-up of 5.0 y (0-20.5 y), post-HT survival rates at 1, 5, and 10 y were comparable between groups. One-y survival improved from 70% in the early eras to 80% in the current era (hazard ratio [HR], 0.63; 95% confidence interval [CI], 0.41-0.97; Conclusions: Posttransplant survival is comparable between patients with CC, nonischemic cardiomyopathy, and ischemic cardiomyopathy. Although survival has improved significantly over years for most HT recipients, it has remained unchanged for those with Chagas disease. These trends underscore the importance of scientific research, policy discussions and a collaborative registry of heart transplantation in Chagas cardiomyopathy.

Identifiers

PMID35774419
PMCPMC9236606
OpenAlexW4283379133

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.