Evidence map›Paper›PMID 35774397›Full record

ReviewFrontiers in cellular and infection microbiology2022

Mechanisms of SARS-CoV-2 Infection-Induced Kidney Injury: A Literature Review.

Weihang He, Xiaoqiang Liu, Bing Hu, Dongshui Li, Luyao Chen, Yu Li, Yechao Tu, Situ Xiong, Gongxian Wang, Jun Deng and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular and infection microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
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  5. Article
  6. Review
  7. Review
  8. Review
  9. SARS-CoV-2 nucleocapsid protein induces a Mincle-dependent macrophage inflammatory response in acute kidney injury.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Article
  10. Review
  11. Pathological Sequelae of SARS-CoV-2: A Review for Clinicians.The Yale journal of biology and medicine · 2024
    Review
  12. Interactions of SARS-CoV-2 with Human Target Cells-A Metabolic View.International journal of molecular sciences · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Weihang HeReproductive Medicine Center, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Xiaoqiang LiuDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Bing HuDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Dongshui LiReproductive Medicine Center, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Luyao ChenDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Yu LiDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Yechao TuDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Situ XiongDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Gongxian WangDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Jun DengDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Bin FuDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
First Affiliated Hospital of Nanchang University · CNNanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The severe acute respiratory coronavirus 2 (SARS-CoV-2) has become a life-threatening pandemic. Clinical evidence suggests that kidney involvement is common and might lead to mild proteinuria and even advanced acute kidney injury (AKI). Moreover, AKI caused by coronavirus disease 2019 (COVID-19) has been reported in several countries and regions, resulting in high patient mortality. COVID-19-induced kidney injury is affected by several factors including direct kidney injury mediated by the combination of virus and angiotensin-converting enzyme 2, immune response dysregulation, cytokine storm driven by SARS-CoV-2 infection, organ interactions, hypercoagulable state, and endothelial dysfunction. In this review, we summarized the mechanism of AKI caused by SARS-CoV-2 infection through literature search and analysis.

Indexed as

Acute Kidney InjuryCOVID-19HumansKidneyPeptidyl-Dipeptidase ASARS-CoV-2Peptidyl-Dipeptidase AACE2Acute kidney injuryCOVID-19SARS-CoV-2TMPRSS2

Identifiers

PMID35774397
PMCPMC9237415
OpenAlexW4282917097

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.