ArticleBiomedical optics express2022
Tissue-mimicking phantom materials with tunable optical properties suitable for assessment of diffuse reflectance spectroscopy during electrosurgery.
Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 20 citations in OpenAlex.
- Enhancing skin tone representation in optical vascular phantoms.Journal of biomedical optics · 2026Article
- Optical phantoms for the characterization and validation of imaging and spectroscopy: a review.Biophotonics discovery · 2026Review
- Gelatin-Based Head Phantoms: A Practical Guide for Artificial Brain Signal Research.International journal of biomaterials · 2026Article
- A compact, wireless system for continuous monitoring of breast milk expressed during breastfeeding.Nature biomedical engineering · 2025Article
- Development of a multiparameter phantom system for multispectral imaging.Biomedical optics express · 2025Article
- Chitosan-Glycerol Injectable Hydrogel for Intratumoral Delivery of Macromolecules.Gels (Basel, Switzerland) · 2025Article
- Development of silicone-based phantoms for biomedical optics from 400 to 1550 nm.Biomedical optics express · 2024Article
- Design of a wasp-inspired biopsy needle capable of self-propulsion and friction-based tissue transport.Frontiers in bioengineering and biotechnology · 2024Article
- Diffuse reflectance spectroscopy of the spine: improved breach detection with angulated fibers.Biomedical optics express · 2023Article
- Gelatin-containing porous polycaprolactone PolyHIPEs as substrates for 3D breast cancer cell culture and vascular infiltration.Frontiers in bioengineering and biotechnology · 2023Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Emerging intraoperative tumor margin assessment techniques require the development of more complex and reliable organ phantoms to assess the performance of the technique before its translation into the clinic. In this work, electrically conductive tissue-mimicking materials (TMMs) based on fat, water and agar/gelatin were produced with tunable optical properties. The composition of the phantoms allowed for the assessment of tumor margins using diffuse reflectance spectroscopy, as the fat/water ratio served as a discriminating factor between the healthy and malignant tissue. Moreover, the possibility of using polyvinyl alcohol (PVA) or transglutaminase in combination with fat, water and gelatin for developing TMMs was studied. The diffuse spectral response of the developed phantom materials had a good match with the spectral response of porcine muscle and adipose tissue, as well as
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Registered trials
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