ArticleBiomedical optics express2022
Optical-force-controlled red-blood-cell microlenses for subwavelength trapping and imaging.
Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Red Blood Cells as Endogenous Biotweezers for Optical Micromanipulation In Vivo.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Light force-powered cellular medical micromachines.Frontiers in bioengineering and biotechnology · 2026Review
- Advances in Microfluidics for Single Red Blood Cell Analysis.Biosensors · 2023Review
- Biological Cells as Natural Biophotonic Devices: Fundamental and Applications-introduction to the feature issue.Biomedical optics express · 2022Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We demonstrate that red blood cells (RBCs), with an adjustable focusing effect controlled by optical forces, can act as bio-microlenses for trapping and imaging subwavelength objects. By varying the laser power injected into a tapered fiber probe, the shape of a swelled RBC can be changed from spherical to ellipsoidal by the optical forces, thus adjusting the focal length of such bio-microlens in a range from 3.3 to 6.5 µm. An efficient optical trapping and a simultaneous fluorescence detecting of a 500-nm polystyrene particle have been realized using the RBC microlens. Assisted by the RBC microlens, a subwavelength imaging has also been achieved, with a magnification adjustable from 1.6× to 2×. The RBC bio-microlenses may offer new opportunities for the development of fully biocompatible light-driven devices in diagnosis of blood disease.
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Registered trials
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