ArticleBiomedical optics express2022
Monte-Carlo simulation and tissue-phantom model for validation of ocular oximetry.
Article in Biomedical optics express, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 16 citations in OpenAlex.
- Dual-threshold adaptive irradiation strategy for vascular-targeted photodynamic therapy based on hyperspectral-photoacoustic dual-modality imaging.Biomedical optics express · 2026Article
- Light transport in the human spine for optical bone density assessment: Monte Carlo modeling and validation.Biomedical optics express · 2025Article
- Retinal changes detected by diffuse reflectance spectroscopy in parkinsonian monkeys.Neurophotonics · 2025Article
- Evaluation of macular retinal oximetry across different levels of diabetic retinopathy: a cross sectional study.BMC ophthalmology · 2025Article
- Test-retest repeatability in macular retinal oximetry.Clinical & experimental optometry · 2024Article
- Variations in Retinal Oxygen Saturation in a Diverse Healthy Population.Clinical optometry · 2024Article
- Targeted spectroscopy in the eye fundus.Journal of biomedical optics · 2023Article
- Sensitivity of visible range multi-wavelength algorithms for retinal tissue oximetry to acquisition parameters.Biomedical optics express · 2023Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ocular oximetry, in which blood oxygen saturation is evaluated in retinal tissues, is a promising technique for the prevention, diagnosis and management of many diseases and conditions. However, the development of new tools for evaluating oxygen saturation in the eye fundus has often been limited by the lack of reference tools or techniques for such measurements. In this study, we describe a two-step validation method. The impact of scattering, blood volume fraction and lens yellowing on the oximetry model is investigated using a tissue phantom, while a Monte Carlo model of the light propagation in the eye fundus is used to study the effect of the fundus layered-structure. With this method, we were able to assess the performance of an ocular oximetry technique in the presence of confounding factors and to quantify the impact of the choroidal circulation on the accuracy of the measurements. The presented strategy will be useful to anyone involved in studies based on the eye fundus diffuse reflectance.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.