Evidence map›Paper›PMID 35774224›Full record

ArticleFrontiers in cell and developmental biology2022

Neuronal Cell Differentiation of Human Dental Pulp Stem Cells on Synthetic Polymeric Surfaces Coated With ECM Proteins.

Yan Gao, Zeyu Tian, Qian Liu, Ting Wang, Lee-Kiat Ban, Henry Hsin-Chung Lee, Akihiro Umezawa, Abdulrahman I Almansour, Natarajan Arumugam, Raju Suresh Kumar and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 4 countries.

Yan GaoSchool of Biomedical Engineering, The Eye Hospital of Wenzhou Medical University, Wenzhou Medical University, Wenzhou, China.
Zeyu TianSchool of Biomedical Engineering, The Eye Hospital of Wenzhou Medical University, Wenzhou Medical University, Wenzhou, China.
Qian LiuSchool of Biomedical Engineering, The Eye Hospital of Wenzhou Medical University, Wenzhou Medical University, Wenzhou, China.
Ting WangSchool of Biomedical Engineering, The Eye Hospital of Wenzhou Medical University, Wenzhou Medical University, Wenzhou, China.
Lee-Kiat BanDepartment of Surgery, Hsinchu Cathay General Hospital, Hsinchu, Taiwan.
Henry Hsin-Chung LeeDepartment of Surgery, Hsinchu Cathay General Hospital, Hsinchu, Taiwan.
Akihiro UmezawaDepartment of Reproduction, National Center for Child Health and Development, Tokyo, Japan.
Abdulrahman I AlmansourDepartment of Chemistry, College of Sciences, King Saud University, Riyadh, Saudi Arabia.
Natarajan ArumugamDepartment of Chemistry, College of Sciences, King Saud University, Riyadh, Saudi Arabia.
Raju Suresh KumarDepartment of Chemistry, College of Sciences, King Saud University, Riyadh, Saudi Arabia.
Qingsong YeCenter of Regenerative Medicine, Renmin Hospital of Wuhan University, Wuhan, China.
Akon HiguchiSchool of Biomedical Engineering, The Eye Hospital of Wenzhou Medical University, Wenzhou Medical University, Wenzhou, China.
Hao ChenSchool of Biomedical Engineering, The Eye Hospital of Wenzhou Medical University, Wenzhou Medical University, Wenzhou, China.
Tzu-Cheng SungSchool of Biomedical Engineering, The Eye Hospital of Wenzhou Medical University, Wenzhou Medical University, Wenzhou, China.
Wenzhou Medical University · CNKing Saud University · SAAffiliated Eye Hospital of Wenzhou Medical College · CNCathay General Hospital · TWNational Center For Child Health and Development · JPNational Central University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stem cells serve as an ideal source of tissue regeneration therapy because of their high stemness properties and regenerative activities. Mesenchymal stem cells (MSCs) are considered an excellent source of stem cell therapy because MSCs can be easily obtained without ethical concern and can differentiate into most types of cells in the human body. We prepared cell culture materials combined with synthetic polymeric materials of poly-N-isopropylacrylamide-co-butyl acrylate (PN) and extracellular matrix proteins to investigate the effect of cell culture biomaterials on the differentiation of dental pulp stem cells (DPSCs) into neuronal cells. The DPSCs cultured on poly-L-ornithine (PLO)-coated (TPS-PLO) plates and PLO and PN-coated (TPS-PLO-PN) plates showed excellent neuronal marker (

Indexed as

cell therapydental pulp stem cellsneuronal cell differentiationpoly-L-ornithinepoly-N-isopropylacrylamide-butyl acrylatesynthetic cell culture polymer

Identifiers

PMID35774224
PMCPMC9237518
OpenAlexW4282837084

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.