Evidence map›Paper›PMID 35774100›Full record

ArticleFrontiers in pediatrics2022

The Growing Spectrum of DADA2 Manifestations-Diagnostic and Therapeutic Challenges Revisited.

Carolin Escherich, Benedikt Bötticher, Stefani Harmsen, Marc Hömberg, Jörg Schaper, Myriam Ricarda Lorenz, Klaus Schwarz, Arndt Borkhardt, Prasad Thomas Oommen

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pediatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Carolin EscherichDepartment of Pediatric Oncology, Hematology and Clinical Immunology, University Hospital, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Benedikt BötticherDepartment of Pediatric Oncology, Hematology and Clinical Immunology, University Hospital, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Stefani HarmsenDepartment of General Pediatrics, Neonatology and Pediatric Cardiology, University Hospital, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Marc HömbergDepartment of Pediatric Hematology and Oncology, Medical Faculty, University of Cologne, Cologne, Germany.
Jörg SchaperDepartment of Diagnostic and Interventional Radiology, Medical Faculty, University Hospital, Heinrich Heine University, Düsseldorf, Germany.
Myriam Ricarda LorenzInstitute for Transfusion Medicine, University Hospital, Medical Faculty, Ulm University, Ulm, Germany.
Klaus SchwarzInstitute for Transfusion Medicine, University Hospital, Medical Faculty, Ulm University, Ulm, Germany.
Arndt BorkhardtDepartment of Pediatric Oncology, Hematology and Clinical Immunology, University Hospital, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Prasad Thomas OommenDepartment of Pediatric Oncology, Hematology and Clinical Immunology, University Hospital, Medical Faculty, Heinrich Heine University, Düsseldorf, Germany.
Düsseldorf University Hospital · DEHeinrich Heine University Düsseldorf · DEUniversity Hospital Ulm · DEUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deficiency of Adenosine Deaminase Type 2 (DADA2) is a rare autosomal recessive inherited disorder with a variable phenotype including generalized or cerebral vasculitis and bone marrow failure. It is caused by variations in the adenosine deaminase 2 gene (

Indexed as

ADA2 enzyme activitydeficiency of adenosine deaminase type 2diagnostic algorithmphenotype-genotype diversitysiblings at risk

Identifiers

PMID35774100
PMCPMC9237362
OpenAlexW4282821805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.