Evidence map›Paper›PMID 35774083›Full record

ReviewFrontiers in cellular neuroscience2022

Progress on Designing a Chemical Retinal Prosthesis.

Jiajia Wu, Corey M Rountree, Sai-Siva Kare, Pradeep Kumar Ramkumar, John D Finan, John B Troy

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cellular neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jiajia WuDepartment of Biomedical Engineering, Robert R. McCormick School of Engineering and Applied Science, Northwestern University, Evanston, IL, United States.
Corey M RountreeDepartment of Mechanical and Industrial Engineering, College of Engineering, University of Illinois at Chicago, Chicago, IL, United States.
Sai-Siva KareDepartment of Mechanical and Industrial Engineering, College of Engineering, University of Illinois at Chicago, Chicago, IL, United States.
Pradeep Kumar RamkumarDepartment of Mechanical and Industrial Engineering, College of Engineering, University of Illinois at Chicago, Chicago, IL, United States.
John D FinanDepartment of Mechanical and Industrial Engineering, College of Engineering, University of Illinois at Chicago, Chicago, IL, United States.
John B TroyDepartment of Biomedical Engineering, Robert R. McCormick School of Engineering and Applied Science, Northwestern University, Evanston, IL, United States.
University of Illinois Chicago · USNorthwestern University · US

Funding

Enabling Technology for a Biomimetic Artificial Retinal Chemical Synapse ChipR21EB028069 · NIBIB · UNIVERSITY OF ILLINOIS AT CHICAGO · PI FINAN, JOHN D · 2019 to 2020
$639k
NIBIB NIH HHS R21 EB028069
6 · The paper itself

Abstract

The last major review of progress toward a chemical retinal prosthesis was a decade ago. Many important advancements have been made since then with the aim of producing an implantable device for animal testing. We review that work here discussing the potential advantages a chemical retinal prosthesis may possess, the spatial and temporal resolutions it might provide, the materials from which an implant might be constructed and its likely effectiveness in stimulating the retina in a natural fashion. Consideration is also given to implant biocompatibility, excitotoxicity of dispensed glutamate and known changes to photoreceptor degenerate retinas.

Indexed as

glutamate stimulationneurotransmitter-based prosthesisretinal degenerationretinal prosthesisretinitis pigmentosavision restoration

Identifiers

PMID35774083
PMCPMC9239740
OpenAlexW4281697538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.