ArticleFrontiers in bioengineering and biotechnology2022
Opposite Effect of Cyclic Loading on the Material Properties of Medial Collateral Ligament at Different Temperatures: An Animal Study.
Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 5 citations in OpenAlex.
- Rotator Cuff Tear-induced Changes in Tendon Structure and Mechanics Measured by Quantitative Magnetic Resonance Imaging.Annals of biomedical engineering · 2025Article
- Initiation and progression of rotator cuff tears due to fatigue loading: a cadaveric study.JSES international · 2025Article
- Influence of walking on knee ligament response in car-to-pedestrian collisions.Frontiers in bioengineering and biotechnology · 2023Article
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Authors and funding
2 authors at 1 institution in 1 country.
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Abstract
In traffic accidents, the medial collateral ligament (MCL) injury of the knee joint of pedestrians is common. Biofidelic material is important to realize MCL's native biomechanics in simulations to clarify the injury mechanisms of pedestrians. Pedestrians' MCLs usually experience cyclic loading at the intra-articular temperature of the knee joint before accidents. Temperature influences the material behaviors of ligaments. However, the mechanical properties of ligaments under cyclic loading have been widely evaluated only at room temperature rather than physiological temperature. Therefore, this study aimed to determine whether the difference between room and intra-articular temperatures influences the effect of cyclic loading on the mechanical properties of MCL. We measured the tensile properties of 34 porcine MCLs at room temperature (21-23°C) and intra-articular temperature (35-37°C), with either 10 cycles or 240 cycles of cyclic loading, a total of four different conditions. The structural responses and geometric data were recorded. After 240 cycles of cyclic loading, stiffness increased by 29.0% (
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