ArticleJournal of Korean Neurosurgical Society2022
Gamma Knife Radiosurgery for Trigeminal Neuralgia : Review and Update.
Article in Journal of Korean Neurosurgical Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.
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Who cites it
11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 16 citations in OpenAlex.
- Neural pathway-guided radiosurgery: A systematic review and meta-analysis of diffusion tensor imaging applications in stereotactic radiosurgery.Neurosurgical review · 2026Pooled it
- Repeat gamma knife radiosurgery for recurrent trigeminal neuralgia: a systematic review and meta-analysis.Acta neurochirurgica · 2026Pooled it
- Review
- Treatment of Typical and Atypical Trigeminal Neuralgia with LINAC-Based Radiosurgery: Complications, Recurrence Rates and Long-Term Treatment Outcomes.Journal of clinical medicine · 2026Article
- Article
- Medically Refractory Trigeminal Neuralgia: A Comparative Study of Outcomes of Microvascular Decompression versus Gamma Knife Radiosurgery and Percutaneous Radiofrequency Ablation.Journal of neurological surgery. Part B, Skull base · 2026Article
- Biologically Effective Dose and Dose Rate in Gamma Knife Radiosurgery for Trigeminal Neuralgia: A Systematic Review and Meta-Analysis.Advances in radiation oncology · 2026Review
- Treatment strategy in stereotactic radiosurgery for trigeminal neuralgia, essential tremor, and coexisting intracranial tumors: The impact of biologically effective dose on clinical outcome.Journal of applied clinical medical physics · 2026Article
- Article
- Article
- Navigating precision: Anatomical insights into the efficacy of masks versus stereotactic frames in icon gamma knife treatment for trigeminal neuralgia.Surgical neurology international · 2025Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Accurate diagnosis of trigeminal neuralgia (TN) is the starting point for optimal treatment. Gamma knife radiosurgery (GKRS) is currently regarded as one of the first-line treatment options for medically refractory TN. GKRS is a less invasive treatment with a low risk of complications than other surgical procedures that provides a favorable pain control (BNI I-IIIb) rate of >75% at short-term follow-up. Drawbacks of GKRS include the latency period before pain relief and higher recurrence rate compared with microvascular decompression. Therefore, repeat treatment is necessary if the initial GKRS was effective but followed by recurrence. The concept of dose rate and the biologically effective dose of radiation has been actively studied in radiation oncology and is also applied in GKRS for TN to achieve high safety and efficacy by prescribing the optimal dose. Recent progress in functional imaging, such as diffusion tensor imaging, enables us to understand the pathophysiology of TN and predict the clinical outcome after GKRS. Here, we review TN, GKRS, and recent updates, especially in the concepts of radiation dose, diffusion tensor imaging studies, and repeat treatment in GKRS for TN.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.