ArticlePediatric pulmonology2022
Breath-dependent pressure fluctuations in various constant- and variable-flow neonatal CPAP devices.
Article in Pediatric pulmonology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 8 citations in OpenAlex.
- Neonatal bench study of a constant-flow device.Pediatric research · 2026Article
- Imposed work of breathing of 16 neonatal CPAP-devices using different mechanisms of CPAP generation.Pediatric research · 2026Article
- What CPAP to use in the delivery room? Bench comparison of two methods to provide continuous positive airways pressure in neonates.BMJ paediatrics open · 2024Article
- Function of neonatal CPAP systems and the importance of total flow.Pediatric pulmonology · 2023Article
- Breath-dependent pressure fluctuations in various constant- and variable-flow neonatal CPAP devices.Pediatric pulmonology · 2022Article
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6 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
objectiveIn continuous positive airway pressure (CPAP) devices, pressure can be generated by two different mechanisms: either via an expiratory valve or by one or more jets. Valved CPAP devices are referred to as constant-flow devices, and jet devices are called variable-flow devices. Constant-flow CPAP devices are said to reduce the imposed work of breathing due to lower breath-dependent pressure fluctuations. The present study investigates the performance of various constant- and variable-flow CPAP devices in relation to breath-dependent pressure fluctuations.
designExperimental study comparing the pressure fluctuations incurred by seven neonatal CPAP devices attached to an active neonatal lung model. METHODOLOGY: Spontaneous breathing was simulated using a tidal volume of 6 ml at pressure levels of 5, 7, and 9 mbar. The main outcomes were respiratory pressure fluctuations, tidal volume, and end-expiratory pressure.
resultsAll CPAP devices tested showed respiratory pressure fluctuations, varying from 0.631 to 3.466 mbar. The generated tidal volume correlated significantly with the pressure fluctuations (r = -0.947; p = 0.001) and varied between 5.550 and 6.316 ml. CPAP devices with jets showed no advantage over CPAP devices with expiratory valves. End-expiratory pressure in the nose deviated from the set pressure between -1.305 and 0.644 mbar and varied depending on whether the pressure was measured in the device or in the tube extending to the nose.
conclusionDuring standard spontaneous breathing, breath-dependent pressure fluctuations in constant- and variable-flow devices are comparable. Pressure measurements taken in the tubing system can lead to a considerable deviation of the applied pressure.
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