ReviewClinical epigenetics2022
DNA methylation: a potential mediator between air pollution and metabolic syndrome.
Review in Clinical epigenetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 60 citations in OpenAlex.
- Seasonal PMToxics · 2026Article
- Association between PMFrontiers in public health · 2026Article
- Long-term exposure to ambient air pollutant mixture and metabolic obesity phenotypes: Results from a nationwide Korean study (2007-2019).Journal of exposure science & environmental epidemiology · 2026Article
- Climate informed precision health.Frontiers in public health · 2026Article
- Timing of dietary effects on the epigenome and their potential protective effects against toxins.Epigenetics · 2025Review
- Air Pollution Exposure and Muscle Mass and Strength Decline in Older Adults: Results From a Swedish Population-Based Study.Journal of cachexia, sarcopenia and muscle · 2025Article
- Prenatal Nitrogen Oxide (NOEnvironmental science & technology · 2025Article
- Exploring the link between environmental chemical exposures and epigenetic modifications in diabetes mellitus: A review.Biomolecules & biomedicine · 2025Review
- Long-Term Exposure to Ambient Air Pollution and Metabolic Syndrome and Its Components.Journal of obesity & metabolic syndrome · 2025Review
- Causal association between PMScientific reports · 2025Article
- Association between annual concentration of air pollutants and incidence of metabolic syndrome among Korean adults: Korean Genome and Epidemiology Study (KoGES).Environmental health : a global access science source · 2025Article
- Epigenetics of Chronic Stress: Mechanisms and Health Impacts.Current genomics · 2025Review
- Exploring genetic susceptibility to air pollution and its implications for disease risk and precision health: A scoping review.AIMS public health · 2025Review
- Exposure to air pollution increases susceptibility to ulcerative colitis through epigenetic alterations in CXCR2 and MHC class III region.EBioMedicine · 2024Article
- Mechanistic insights regarding neuropsychiatric and neuropathologic impacts of air pollution.Critical reviews in toxicology · 2024Review
- Individual and joint exposure to air pollutants and patterns of multiple chronic conditions.Scientific reports · 2024Article
- Review
- Does Serum Uric Acid Mediate Relation between Healthy Lifestyle and Components of Metabolic Syndrome?Nutrients · 2024Article
- Deciphering the complex interplay of risk factors in type 2 diabetes mellitus: A comprehensive review.Metabolism open · 2024Review
- Methods for the Analysis of Multiple Epigenomic Mediators in Environmental Epidemiology.Current environmental health reports · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Given the global increase in air pollution and its crucial role in human health, as well as the steep rise in prevalence of metabolic syndrome (MetS), a better understanding of the underlying mechanisms by which environmental pollution may influence MetS is imperative. Exposure to air pollution is known to impact DNA methylation, which in turn may affect human health. This paper comprehensively reviews the evidence for the hypothesis that the effect of air pollution on the MetS is mediated by DNA methylation in blood. First, we present a summary of the impact of air pollution on metabolic dysregulation, including the components of MetS, i.e., disorders in blood glucose, lipid profile, blood pressure, and obesity. Then, we provide evidence on the relation between air pollution and endothelial dysfunction as one possible mechanism underlying the relation between air pollution and MetS. Subsequently, we review the evidence that air pollution (PM, ozone, NO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.