ArticleBMC geriatrics2022
Associations between loneliness and frailty among older adults: Evidence from the China Health and Retirement Longitudinal Study.
Article in BMC geriatrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Intervention for Social Frailty Focusing on Physical Activity and Reducing Loneliness: A Randomized Controlled Trial.Clinical interventions in aging · 2025Trial
- Loneliness in prostate cancer survivors.Journal of cancer research and clinical oncology · 2026Article
- Longitudinal bidirectional associations among sarcopenia risk, social isolation, and frailty in Chinese older adults using an item response theory-derived frailty index.Frontiers in public health · 2026Observational
- Internet use and frailty in Chinese middle-aged and older adults: empirical evidence from CHARLS 2020.BMC public health · 2025Article
- Unravelling the association between internet use and loneliness among Chinese older adults during the COVID-19 pandemic: the role of potentially moderating and mediating factors.BMC geriatrics · 2025Article
- Frailty and loneliness among community-dwelling older adults: examining reciprocal associations within a measurement burst design.BMC geriatrics · 2025Article
- Early Recognition of Loneliness and Frailty in Relation to Chronic Disease Self-Management: A Quantitative Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2025Article
- Late-Life Informal Social Participation, Physical and Cognitive Functions Among the Chinese Elderly: A Life Course Perspective.Healthcare (Basel, Switzerland) · 2025Article
- Association between household solid fuel use and cognitive frailty in a middle-aged and older Chinese population.Frontiers in public health · 2025Article
- Article
- Explainable machine learning model for pre-frailty risk assessment in community-dwelling older adults.Health care science · 2024Article
- Sequential multiple mediating effect of loneliness and family health on physical frailty and willingness to age at home in older adults: a national survey in China.BMC geriatrics · 2024Article
- The Impact of Social Participation on Frailty among Older Adults: The Mediating Role of Loneliness and Sleep Quality.Healthcare (Basel, Switzerland) · 2024Article
- The temporal sequence and reciprocal relationships of frailty, social isolation and loneliness in older adults across 21 years.Age and ageing · 2024Article
- The association between loneliness and frailty among community-dwelling older adults in five European countries: a longitudinal study.Age and ageing · 2024Article
- Frailty and Loneliness in Older Adults: A Narrative Review.Geriatrics (Basel, Switzerland) · 2024Review
- Understanding the Effect of Loneliness on Quality of Life in Older Adults from Longitudinal Approaches.Psychosocial intervention · 2024Article
- Frailty Assessment and Its Impact on Loneliness among Older Adults Receiving Home-Based Healthcare during the COVID-19 Pandemic.Healthcare (Basel, Switzerland) · 2024Article
- The association of social isolation and loneliness with sarcopenia among the middle-aged and elderly in China.BMC psychiatry · 2024Article
- Changes in frailty and depressive symptoms among middle-aged and older Chinese people: a nationwide cohort study.BMC public health · 2024Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious studies have demonstrated the associations between loneliness and frailty in late life. However, there is a lack of consensus on the direction of the relationship. The present study aimed to examine the interdependencies between loneliness and frailty over time.
methodsData on participants aged 60 years old and above were collected from the 2011, 2013, and 2015 samples of the China Health and Retirement Longitudinal Study (CHARLS). Loneliness was measured by a single question from the Centre for Epidemiological Studies Depression scale, and frailty was assessed by the Physical Frailty Phenotype (PFP) scale. Cross-lagged panel models were utilized to examine the potential bidirectional relationship between loneliness and frailty.
resultsReciprocal associations were found between loneliness and frailty. Furthermore, we found that baseline frailty and early change in frailty had a significant predictive effect on late change in loneliness. Higher baseline loneliness in older adults may create a potentially vicious cycle that influenced early change in frailty and continued to cause late change in loneliness.
conclusionA bidirectional relationship may exist between loneliness and frailty among older Chinese adults over 60 years old. Lonely older adults should be alerted to the potential self-reinforcing cycle of loneliness that affects their health.
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