Evidence map›Paper›PMID 35773610›Full record

ArticleMedical & biological engineering & computing2022

Expandable pedicle screw may have better fixation than normal pedicle screw: preclinical investigation on instrumented L4-L5 vertebrae based on various physiological movements.

Devismita Sanjay, Jaideep Singh Bhardwaj, Neeraj Kumar, Souptick Chanda

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Article in Medical & biological engineering & computing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Devismita SanjayDepartment of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, 781 039, Assam, India.
Jaideep Singh BhardwajDepartment of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, 781 039, Assam, India.
Neeraj KumarDepartment of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, 781 039, Assam, India.
Souptick ChandaDepartment of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati, 781 039, Assam, India. csouptick@iitg.ac.in.ORCID http://orcid.org/0000-0002-4110-3191
Indian Institute of Technology Guwahati · IN

Funding

Science and Engineering Research Board SRG/2019/000235
6 · The paper itself

Abstract

Lumbar spine fracture is typically treated by means of screw fixation, the primary aim of which is to reduce fracture by achieving bony union such that the spinal anatomy is restored. Pedicle screw fixation has certain advantages over conventional vertebral screws, e.g. 3-column fixation and improved surgical alignment. However, expandable pedicle screws have been reported to impart better anchorage as compared to conventional pedicle screws, both in case of healthy and osteoporotic bone. The clinical studies notwithstanding, there is a paucity of preclinical investigations on expandable pedicle screws used on lumbar vertebrae. By employing anatomically viable FE models, the present study intended to estimate stress-strain fields of a functional spinal unit (FSU) of intact L4-L5 vertebra and to further compare the same with FSUs instrumented with normal and expandable pedicle screws under different physiological loading condition. The various physiological loading regimes appeared to have significant influence on the overall load transfer in the L4-L5 vertebrae. The expandable pedicle screw predicted marginally improved anchorage as compared to the normal pedicle screws, with more contact area with the bone resulting in higher stresses (~ 1.6 MPa) and high strain at the contact sites. This is indicative of improved stability albeit having marginally greater risk of screw pullout. Greater area (15-80%) with peak stresses at the bone-screw interfaces also indicates lesser degree of stress shielding. Thus, stability aside, one may expect to have lower loosening issues too with the use of expandable pedicle screws.

Indexed as

Pedicle ScrewsSpinal FracturesSpinal FusionBiomechanical PhenomenaHumansLumbar VertebraeBiomechanicsFinite element analysisFracture fixationPedicle screwSpine

Identifiers

PMID35773610
OpenAlexW4283734145

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.